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NCT Number: NCT06753838

Choice of Anticoagulant for Primary Hemostasis Studies With PFA200® (Platelet Function Analyser)

The PFA (platelet function analysis) test is prescribed for the exploration of primary hemostasis and the study of platelet-willebrand factor interaction. It is performed using citrated blood, with technical difficulties and frequent alarms that may be linked to the choice of anticoagulant (citrate). It is proposed to compare the results obtained with a conventional citrate tube and a BAPA tube, which is an anticoagulant used in clinical research and which blocks coagulation by another mechanism that would have less impact on blood platelets.

Recruiting

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Key information

Conditions

Hemostasis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Person having given their non-opposition
  • Person of legal age
  • Person receiving a haemostasis consultation at the haemophilia and haemorrhagic diseases treatment center followed by a blood sample with a PFA test prescribed by the doctor (the test is not added for the study).

Exclusion criteria

  • persons under legal protection (curatorship, guardianship)
  • persons subject to a court protection order
  • pregnant, parturient or breast-feeding women
  • adult incapable or unable to give consent
  • minor

Treatment and study plan

Sampling of 3 additional BAPA tubes

Biological

the 3 additional tubes will be taken at the same time as the blood sample taken for the routine PFA test

Primary outcomes

  1. Occlusion time measurement

    Time frame: at baseline

    Measurement of the occlusion times of the 2 cartridges (collagen/ADP and collagen/epinephrine) with the classic 0.109M citrate tube and the BAPA tube, with any PLC alarms and observation of the stained blood smears.

Study contacts

Contact information is provided by the study sponsor or research team.

Emmanuel De Maistre

CONTACT

[email protected]

03 80 29 32 57

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire Dijon

Other

Registry information

Acronym: BAPAPFA

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Dec 31, 2024
Registry last updated
Sep 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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