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NCT Number: NCT06491992

Chitosan Phonophresis on Cervical IN Smartphone Addicted Users

A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored in various biomaterial and medical applications. Chitosan has emerged as a cost-effective, biocompatible, and biodegradable material with many desirable biological properties, improvement of homeostasis and antiviral potential. Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema, the polycationic nature of chitosan allows it to absorb protons, which reduces inflammation and provides an analgesic effect.

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Key information

Conditions

Cervical Pain Neck Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

16 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Lama S Mahmoud

Al Jīzah, Select State, Egypt

Location status: Recruiting

Location contact

Lama S Mahmoud

CONTACT

[email protected]

01157592636

About this study

The patients will randomly be divided into two equal groups; the control group which will receive the selected exercise program and the study group will receive the same exercise training program in addition to Chitosan Phonophresis, three times per week for four weeks.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Their age will be ranged from 16-18 years
  • body mass index will be 26.58 kg/m2.
  • used a smart phone for more than 1 year for at least 2 hours per day
  • complaining of neck pain after using a smart phone, addiction to smart phone in accordance with the smart phone addiction scale (SAS)

Exclusion criteria

  • any previous head and neck injuries or surgeries
  • any congenital abnormalities or symptomatic deformity in either the cervical or the lumbar spine
  • any uncorrected visual or auditory problems, dizziness, vertigo and headache
  • any systematic diseases, any addiction to alcohol, any additive drugs and sedatives within 48 hours previous to tests
  • body mass index of subjects over25 kg/m2.

Treatment and study plan

Chitosan Phonophresis

Drug

Chitosan Phonophresis, three times per week for four weeks.

selected physical therapy exercise

Other

selected neck exercise and electrotherapy on cervical region

Primary outcomes

  1. Smartphone Addiction Scale-Short Version (SAS-SV)

    Time frame: four weeks

    SAS-SV was psychometrically robust in measuring the severity of smartphone addiction

  2. The visual analogue scale

    Time frame: four weeks

    was utilized to evaluate pre- and post-treatment neck pain

  3. Neck disability index

    Time frame: four weeks

    assess how neck pain and other symptoms manifested during various functional activities. Ndi had been reported as a reliable (Cronbach's alpha: 0.89) and valid instrument to evaluate self-rated disability in patients with neck pain

Secondary outcomes

  1. Cervical ROM

    Time frame: four weeks

    Cervical active ROM will be measured for each participant in the study by digital goniometer device.

Study contacts

Contact information is provided by the study sponsor or research team.

Lama Saad El-Din ED Mahmoud

CONTACT

[email protected]

01157592636

Sponsors and collaborators

Lead sponsor

October 6 University

Other

Registry information

Official study title

Effect of Chitosan Phonophresis on Cervical Pain and Disability in Smartphone Addicted Users

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jul 9, 2024
Registry last updated
Jul 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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