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NCT Number: NCT06954727

China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-right Heart Catheterization

Right heart catheterization(RHC) plays a crucial role in the diagnosis and treatment of pulmonary vascular diseases(PVD). In China, the lack of equipment and technical expertise has historically limited the implementation of RHC, thereby greatly restricting the diagnosis and treatment of RVD. In recent years, with improvements in these issues, more hospitals have acquired the capability to perform RHC. The purpose of this study is to conduct quality control of RHC across multiple pulmonary hypertension(PH) centers in China. The study population consists of patients who underwent RHC for the first time due to dyspnea or suspected PH. This study retrospectively and prospectively collects multicenter RHC data, with the main quality control contents including indications for the procedure, collection and analysis of hemodynamic data, diagnosis and treatment, and long-term management of patients.

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Key information

Conditions

Pulmonary Hypertension Cardiovascular Diseases Disease Embolism Embolism and Thrombosis Hypertension Hypertension, Pulmonary Lung Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Arterial Hypertension Pulmonary Embolism Pulmonary Embolism (Diagnosis) Respiratory Tract Diseases Right Heart Catheterization Vascular Diseases

Age range

14 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

This study is led by the China-Japan Friendship Hospital and will be conducted across approximately 30 pulmonary hypertension centers in China. It is an observational cohort study without interventional treatment. Eligible participants are patients aged 14 years or older who undergo right heart catheterization due to dyspnea or suspected pulmonary hypertension. After study initiation, investigators at each center will enroll eligible patients and collect baseline data, hemodynamic parameters from right heart catheterization, diagnostic classification of pulmonary hypertension, and treatment plans. Patients will receive routine follow-up at their respective centers, and investigators will gather follow-up data according to the study protocol. All de-identified data will be recorded in an Electronic Data Capture (EDC) system. A dedicated data management team will oversee data management, quality control, and statistical analysis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who underwent right heart catheterization for the first time due to dyspnea or suspected pulmonary hypertension
  • Age ≥14 years old

Exclusion criteria

  • Vital data missing
  • Did not sign informed consent or did not agree to follow-up

Treatment and study plan

No intervention; Observational study

Other

No intervention; observational study

Primary outcomes

  1. 3-month all cause death

    Time frame: 3 month

    3-month all cause death

Secondary outcomes

  1. dignosis and type of pulmonary hypertension

    Time frame: 1 month

    dignosis and type of pulmonary hypertension according to latest guidelines

  2. 1-year all cause death

    Time frame: 1 year

    1-year all cause death

Study contacts

Contact information is provided by the study sponsor or research team.

Yu Zhang, MD

CONTACT

[email protected]

+8613120211583

Zhenguo Zhai

CONTACT

[email protected]

010-8420-6265

Sponsors and collaborators

Lead sponsor

China-Japan Friendship Hospital

Other

Registry information

Official study title

China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-A Quality Control on Right Heart Catheterization

Acronym: CHA-RHC

Important dates

Study start
2018
Primary completion
2028
Study completion
2030
First posted
May 2, 2025
Registry last updated
May 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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