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NCT Number: NCT03699228

China Health Big Data

In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. The aim of this study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

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Key information

Conditions

Osteoporosis Body Weight Bone Diseases Bone Diseases, Metabolic Digestive System Diseases Fatty Liver Liver Diseases Liver Steatoses Metabolic Diseases Musculoskeletal Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

30 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Wu Hu Yijishan Hospital, Wuhu, Anhui, China

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About this study

Low dose Chest CT scan is the standard for lung cancer in the health check center in China. Quantitative computed tomography (QCT) is utilizing the CT raw data to measure the bone mineral density (BMD), the visceral fat (VAT) and liver fat content in human, which can be widely used in the diagnosis of osteoporosis, the assessment of obesity and liver steatosis. In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. This study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

health check subjects 30-90 years old low dose chest CT scan

Exclusion criteria

pregnant women metal implant in the CT scan area

Treatment and study plan

Primary outcomes

  1. The spinal volumetric bone mineral density (vBMD)

    Time frame: 2 year

    The volumetric bone mineral density of L1-2 measured by QCT

Secondary outcomes

  1. The visceral adipose tissue (VAT)

    Time frame: 2 year

    The visceral adipose tissue (VAT) measured by quantitative computed tomography (QCT)

  2. Liver fat

    Time frame: 2 years

    Liver fat measurement by quantitative computed tomography (QCT)

Study contacts

Contact information is provided by the study sponsor or research team.

xiaoguang cheng, md

CONTACT

[email protected]

0086-010-58516947

xiaoxia fu, md

CONTACT

0086-13683132746

Sponsors and collaborators

Lead sponsor

Beijing Jishuitan Hospital

Other

Collaborators

  • China-Japan Friendship Hospital
  • Chinese PLA General Hospital
  • First Affiliated Hospital Xi'an Jiaotong University
  • Henan Provincial People's Hospital
  • Huashan Hospital
  • Nanjing BenQ Hospital
  • Ruijin Hospital
  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
  • The Affiliated Hospital Of Guizhou Medical University
  • The First Affiliated Hospital of Zhengzhou University
  • The fifth affiliated hospital of zhong shan university
  • The renmin hospital of wuhan university
  • Wu Hu Yijishan hospital
  • xinan hospital

Registry information

Official study title

China Nationwide Multi Center Big Data Study on the Quantitative Computed Tomography (QCT) and Health Status of Check -up Population

Acronym: China biobank

Important dates

Study start
2017
Primary completion
2026
Study completion
2026
First posted
Oct 9, 2018
Registry last updated
Aug 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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