nano silver mouthwash
Othernano silver mouthwash will reduce the side effect of chlorhexidine and increase acceptance of the mouthwash to patients
NCT Number: NCT07200063
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine.
Trial opening soon.
Get Notified6 year–12 year
All sexes
Interventional
Not applicable
Effective management of dental plaque is crucial for preventing periodontal diseases, dental caries, and other oral health complications. Oral hygiene can be maintained through both chemical and mechanical methods. Chemical methods are particularly beneficial in situations where mechanical cleaning proves challenging. Mouthwashes represent a significant chemical strategy for controlling plaque. Among different types of mouthwashes, chlorhexidine is considered the gold standard due to its high efficacy against a broad spectrum of bacteria and its role in plaque management, which helps prevent periodontal diseases. However, it is important to note that chlorhexidine has several side effects, such as numbness, changes in taste perception, dental staining, and an unpleasant bitter taste.
In modern applications, nanotechnology is being utilized more frequently, especially with the integration of nanoparticle materials. Silver nanoparticles, in particular, are widely used in the medical field because of their remarkable antibacterial effects on oral biofilms associated with periodontal disease.
Therefore, this research aims to evaluate the children's acceptance of chlorhexidine mouthwash in children compared to a mouthwash containing silver nanoparticles, as well as to assess their respective impacts on gingivitis.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
nano silver mouthwash will reduce the side effect of chlorhexidine and increase acceptance of the mouthwash to patients
the concentration of chlorhexidine
chlorhexidine mouthwash 0.2% (orovex )
Other names: orovex
Time frame: 15 days
it will be measured by likert scale (1-5)
1 (strongly disagree) 5 (strongly agree)
Time frame: 15 days
Time frame: 15 days
Time frame: 15 days
measure color stability of composite restoration of anterior teeth ΔE* = √((L₂ - L₁)² + (a₂ - a₁)² + (b₂ - b₁)²
Where:
L* = Lightness (0 = black, 100 = white)
Contact information is provided by the study sponsor or research team.
Cairo University
Other
Comparative Assessment of Children's Acceptance and Compliance of Mouthwash Containing Silver Nanoparticles Compared to Chlorhexidine Mouthwash: A Randomized Clinical Trial.
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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