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NCT Number: NCT07366216

Chewing Under Dual-Tasking in MS

This study aims to investigate the effects of visual, auditory, and motor dual-task conditions on chewing performance in individuals with multiple sclerosis, compared with healthy controls.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individuals aged between 18 and 65 years
  • Mini-Mental State Examination (MMSE) score of 24 or higher
  • Right-hand dominance

Exclusion criteria

  • Presence of visual and/or hearing impairment
  • Presence of difficulties in solid food intake and/or complaints related to mastication
  • Presence of neurological, psychological, cognitive, and/or chronic conditions that may affect mastication or chewing function
  • History of interventions affecting oral structure (e.g., oral/maxillofacial surgery or radiotherapy) within the last month
  • Known allergy to the food used in the test

Treatment and study plan

Primary outcomes

  1. Test of Masticating and Swallowing Solids

    Time frame: Baseline (single-task and dual-task conditions assessed on the same day)

    Test of Masticating and Swallowing Solids (TOMASS) is a standardized clinical assessment used to evaluate solid bolus mastication and swallowing performance.

  2. Mini-Mental State Examination (MMSE)

    Time frame: Baseline

    The MMSE is a brief, widely used screening tool for assessing global cognitive function.

  3. Go/No-Go Test

    Time frame: Baseline (single-task and dual-task conditions assessed on the same day)

    The Go/No-Go Test is a neuropsychological assessment used to evaluate response inhibition and sustained attention.

  4. Auditory Reaction Time Test

    Time frame: Baseline (single-task and dual-task conditions assessed on the same day)

    The Auditory Reaction Time Test is used to assess auditory attention and the speed of motor response to auditory stimuli.

  5. Tap Tool

    Time frame: Baseline (single-task and dual-task conditions assessed on the same day)

    The Tap Tool is a neuropsychological and motor performance assessment used to evaluate psychomotor speed and fine motor control.

Study contacts

Contact information is provided by the study sponsor or research team.

Seda Nur Kemer, PhD

CONTACT

[email protected]

+905467861866

Sponsors and collaborators

Lead sponsor

Ondokuz Mayıs University

Other

Registry information

Official study title

The Effect of Different Dual-Task Conditions on Chewing Function in Individuals With Multiple Sclerosis

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 26, 2026
Registry last updated
Jan 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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