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OpenTrials
Completed

NCT Number: NCT04485338

Chest Radiography in COVID-19 Patients

To assess the prognostic performance of the RALE score with respect to duration of ventilation, and to describe changes in the RALE score over time.

Completed

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Key information

Conditions

Covid19 COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Nidovirales Infections Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Amsterdam UMC location AMC

Amsterdam, 1105AZ, Netherlands

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Admitted to an ICU participating in this study between December 1, 2019 and May 31, 2020
  • Having had received invasive ventilation
  • Having had received at least one chest radiograph under invasive ventilation
  • Confirmed novel coronavirus diseases (COVID-19)

Exclusion criteria

  • Age < 18 years

Treatment and study plan

Primary outcomes

  1. The prognostic capacity of the Radiographic Assessment of Lung Edema (RALE) score of the first CXR under invasive ventilation in patients with severe COVID-19.

    Time frame: 90 days

Secondary outcomes

  1. The prognostic capacity of changes in the RALE score of consecutive CXRs under invasive ventilation in patients with severe COVID-19

    Time frame: 90 days

  2. Number of ventilator-free day and alive at day 28 (VFD)

    Time frame: 28 days

Sponsors and collaborators

Lead sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Other

Collaborators

  • Chonburi hospital
  • Mahidol University
  • Universitair Ziekenhuis Brussel
  • University of Bari Aldo Moro

Registry information

Official study title

Radiographic Assessment of Lung Edema in Invasively Ventilated COVID-19 Patients (RALE-COVID) - Protocol for an International Multicenter Retrospective Study

Important dates

Study start
2020
Primary completion
2020
Study completion
2021
First posted
Jul 24, 2020
Registry last updated
Feb 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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