Skip to main content
OpenTrials
Completed

NCT Number: NCT04195659

Chest Dysphoria in Transmasculine Spectrum Adolescents

The investigators hypothesize that masculinizing top surgery (e.g., mastectomy and chest masculinization) leads to an improvement in self-report chest dysphoria, gender dysphoria, and gender congruence in assigned-female-at-birth, transgender and non-binary youth and young adults. This is a prospective, observational study that will enroll assigned-female-at-birth, transmasculine spectrum individuals age 13 to 25 years old who are or are not undergoing top surgery. Participants will complete a set of standard of care questionnaires regarding their chest dysphoria (e.g., distress about the chest), gender dysphoria (e.g., distress about a gender identity that does not match assigned sex), and gender congruence (e.g., degree to which an individual feels they are living in their authentic appearance and gender identity). They will complete this same set of questionnaires either three months after their top surgery or three months after the initial set of surveys.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Gender Dysphoria Mental Disorders Sexual Dysfunctions, Psychological

Age range

13 year–25 year

Sex eligibility

Female

Study type

Observational

Primary location

Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Assigned the female sex at birth
  • Affirmed gender identity of male, non-binary, or gender other than female
  • English-speaking
  • Undergoing top surgery or matches a top surgery participant on age and number of months on testosterone

Exclusion criteria

  • Non English speaking
  • Unable to complete self-report questionnaires

Treatment and study plan

Mastectomy and chest masculinization

Procedure

A surgical procedure in which the breasts are removed and the chest is given a masculine contour.

Primary outcomes

  1. Chest Dysphoria

    Time frame: Three month

    The disruption of individual comfort, physical functioning, and interpersonal relationships from a chest with breasts, as measured by the Chest Dysphoria Measure (Score 0-51, Higher number means greater chest dysphoria)

Secondary outcomes

  1. Gender Dysphoria

    Time frame: Three month

    Distress about a gender identity that differs from assigned sex, measured by the Utrecht Gender Dysphoria Scale (Score 12-60, Higher number means greater gender dysphoria)

  2. Gender Congruence

    Time frame: Three month

    Feelings of living in an authentic gender identity and appearance, as measured by the Kozee Transgender Congruence Scale (Score 12-60, Higher number means greater gender congruence)

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Collaborators

  • Ann & Robert H Lurie Children's Hospital of Chicago
  • University of Illinois at Chicago

Registry information

Official study title

The Effect of Top Surgery on Chest Dysphoria in Assigned-Female-At-Birth, Transmasculine Spectrum Youth and Young Adults

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Dec 12, 2019
Registry last updated
Jun 10, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.