Chest CT Scan in Pulmonary Mucormycosis: Prognostic Value

Invasive pulmonary fungal infections caused by Mucorales are rare but severe and rapidly progressive, affecting immunocompromised patients. The role of chest imaging in their diagnosis is well established in the 2020 EORTC/MSGERC criteria, and its use is almost systematic. However, the progression of lung parenchymal involvement and any potential prognostic radiological patterns in the follow-up of these infections are less well understood. This research aims to identify imaging characteristics predictive of favorable or unfavorable outcomes in infected patients, in order to better tailor follow-up and therapeutic options.

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Key information

Conditions

Pulmonary Mucormycosis Bacterial Infections and Mycoses Infections Mycoses

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France

Strasbourg, 67091, France

Location status: Recruiting

Location contact

Baptiste Hoellinger, MD

CONTACT

[email protected]

33 3 69 55 05 45

Baptiste Hoellinger, MD

PRINCIPAL_INVESTIGATOR

Clément XU-VUILLARD, MD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 18 years or older
Treated at Strasbourg University Hospital between January 1, 2009, and June 3, 2025
With a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria
Having undergone at least one CT scan including the thoracic region

Exclusion criteria

No CT scan including the thoracic region
No diagnosis of probable or proven invasive pulmonary infection with Mucorales (EORTC/MSGERC 2020 criteria)

Treatment and study plan

Primary outcomes

Death rate in patients with probable or proven invasive Mucorales infection

Time frame: Day 15 after infection

Death rate at day 15 in patients with probable or proven invasive Mucorales infection

Study contacts

Contact information is provided by the study sponsor or research team.

baptiste Hoellinger, MD

CONTACT

[email protected]

33 3 69 55 05 45

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Acronym: RadioMucor

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Jan 14, 2026
Registry last updated: Jan 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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