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NCT Number: NCT06709989

Chemical and Microbiological Exposure of Women on Dairy Cattle Farms

Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact.

The aim of this research is to gain a better understanding of this chemical and microbiological exposure, and this research focuses in particular on professional women working on dairy cattle farms , who may be in charge of specific activities not commonly carried out by professional men.

Exposure to pesticides, antiparasitic products and disinfectants will be the first substances to be investigated, followed by other chemical or particulate compounds present in everyday and professional environments. Exposure to these compounds will be measured by their presence in the urine, feces (if possible) and hair of around 60 participating women, as well as in bovine tuft/head hair and, if possible, air samples taken in milking buildings.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Occupational Exposure to Chemicals

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

UMR1085 Irset

Rennes, 35000, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult woman working on a dairy cattle farm in the "Grand Ouest" region of France
  • Woman who speaks and understands French

Exclusion criteria

  • working less than 20h/week in dairy farms
  • Woman under legal protection
  • unsigned consent form

Treatment and study plan

Primary outcomes

  1. Exposure to chemicals of women working on dairy farms

    Time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)

    Concentrations of pesticide molecules, biocides, disinfectants and microbiological agents, measured in

    • urines of professional women working on dairy farms,
    • the hair of professional women working on dairy farms,
    • faeces of professional women from dairy farms,
    • tuft/head hair from females in the herd on farms where female professionals work,
    • environmental samples of pesticide molecules (PPPs, pesticides), biocides, disinfectants and microbiological agents.

Secondary outcomes

  1. Exposure to other chemicals

    Time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)

    Concentrations measured in urine, hair, feces, toupillon/head hair and environmental samples from the farm of other chemical compounds present in the participants' professional uses and environments.

Sponsors and collaborators

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Other Gov

Collaborators

  • Ecole des Hautes Etudes en Santé Publique
  • Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Registry information

Official study title

Expositions Chimique et Microbiologique Des Femmes Dans Les Exploitations Bovines laitières

Acronym: DAISY-Expo

Important dates

Study start
2025
Primary completion
2028
Study completion
2028
First posted
Nov 29, 2024
Registry last updated
Mar 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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