Kırşehir Ahi Evran University Training and Research Hospital, Physical Medicine and Rehabilitation Department
Kırşehir, Merkez, 40100, Turkey (Türkiye)
NCT Number: NCT07148687
This study aims to evaluate the effects of rehabilitation programs supported by artificial intelligence-based large language models (LLMs), specifically ChatGPT and DeepSeek, in individuals with subacromial pain syndrome (SAPS). Participants will be randomly assigned to one of three groups: standard physiotherapy, standard physiotherapy plus ChatGPT-guided exercises, and standard physiotherapy plus DeepSeek-guided exercises. Outcomes including pain, disability, quality of life, muscle strength, and joint range of motion will be assessed before and after a 6-week intervention. The results will help determine whether AI-generated exercise recommendations can enhance clinical outcomes when combined with conventional physiotherapy.
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Notify Me18 year–65 year
All sexes
Interventional
Not applicable
Kırşehir, Merkez, 40100, Turkey (Türkiye)
This completed randomized controlled trial investigated the clinical effects of integrating AI-generated exercise recommendations into conventional physiotherapy for individuals with subacromial pain syndrome (SAPS). A total of 82 individuals were assessed for eligibility; 7 were excluded for not meeting inclusion criteria. Seventy-five participants provided consent and were randomized in a 1:1:1 ratio to 3 groups (n=25 each): (1) conventional physiotherapy plus a conventional exercise program, (2) conventional physiotherapy plus ChatGPT-guided exercises, and (3) conventional physiotherapy plus DeepSeek-guided exercises. The allocation sequence was generated using simple computer-based randomization by an independent staff member and was revealed after completion of baseline assessments. Interventions were delivered over 6 weeks (3 supervised sessions/week). Six participants discontinued the intervention due to scheduling conflicts (2 per group). Sixty-nine participants completed the 6-week intervention and were included in the final analysis (n=23 per group). The primary outcome was shoulder pain and disability (Shoulder Pain and Disability Index, SPADI), assessed at baseline and 6 weeks. Secondary outcomes included pain intensity (Numeric Pain Rating Scale, NPRS), health-related quality of life (Short Form-12, SF-12), upper limb function (Disabilities of the Arm, Shoulder and Hand, Quick DASH), range of motion, isometric strength, kinesiophobia, catastrophizing, emotional status, and disease-specific quality of life.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Exercise protocol targeting subacromial pain syndrome, including shoulder mobility, strengthening, and posture correction exercises based on established clinical guidelines.
AI-generated exercise recommendations from ChatGPT-4 tailored to the patient's profile and applied under physiotherapist supervision.
Personalized rehabilitation exercises generated by DeepSeek-R1 and implemented under physiotherapist guidance.
Time frame: Baseline and after 6 weeks of intervention
Disability related to shoulder pain will be measured.Shoulder Pain and Disability Index (0-100; higher scores indicate worse disability).
Time frame: Baseline and after 6 weeks
Functional status of the arm, shoulder, and hand will be assessed using the Disabilities of the Arm, Shoulder and Hand (Quick DASH) questionnaire. Higher scores indicate greater disability.
Time frame: Baseline and after 6 weeks
Active range of motion in shoulder flexion, extension, abduction, internal and external rotation will be measured using a standard manual goniometer.
Time frame: Baseline and after 6 weeks of intervention
Health-related quality of life will be evaluated.Short Form-12 (Physical Component 12-48; Mental Component 12-48; higher scores indicate better quality of life).
Time frame: Baseline and after 6 weeks of intervention
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS) at rest, during activity, and at night. Numeric Pain Rating Scale (0-10; higher scores indicate worse pain).
Time frame: Baseline and after 6 weeks
Isometric muscle strength of shoulder and elbow flexion, extension, and rotation will be assessed using the Kinvent K-Force digital dynamometer. Values will be recorded in Newtons.
Time frame: Baseline and after 6 weeks
Kinesiophobia will be measured using the Tampa Scale for Kinesiophobia (TSK). Tampa Scale for Kinesiophobia (17-68; higher scores indicate greater fear of movement).
Time frame: Baseline and after 6 weeks
Shoulder function will be evaluated using the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES). ASES (0-100; higher scores indicate better shoulder function).
Time frame: Baseline and after 6 weeks of intervention
Pain catastrophizing will be assessed.Pain Catastrophizing Scale (0-52; higher scores indicate worse catastrophizing).
Time frame: Baseline and after 6 weeks of intervention
Anxiety and depression will be evaluated.Hospital Anxiety and Depression Scale (0-21 for Anxiety subscale, 0-21 for Depression subscale; higher scores indicate worse symptoms).
Time frame: Baseline and after 6 weeks of intervention
Disease-specific quality of life in patients with shoulder pathology will be measured.WORC (0-2100; higher scores indicate worse symptoms / lower quality of life).
Kirsehir Ahi Evran Universitesi
Other
Effect of ChatGPT and DeepSeek-Guided Rehabilitation on Clinical Outcomes in Individuals With Subacromial Pain Syndrome
Acronym: LLM-RehabSP
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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