Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong

The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are:

* Whether age would affect outcome * Whether Charlson Comorbidity Index would affect outcome * Whether the conditions (e.g. heart rhythm) immediately before resuscitation would affect survival.

Researchers would compare the patients who deceased with the patients who survived.

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Key information

Conditions

Comorbidities and Coexisting Conditions Cardiopulmonary Resuscitation Geriatrics

Age range

65 year–101 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Haven of Hope Hospital

Hong Kong, China

About this study

The goal of this review was to investigate the impact of age, existing medical conditions. and other factors before cardiac arrest in predicting outcome of in-hospital cardiopulmonary resuscitation (CPR) of older persons.

It was conducted on all patients aged ≥ 65, who underwent CPR in acute medical and geriatric wards (excluding Intensive Care Unit) in United Christian Hospital from January 2017 to December 2018.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
In patients with multiple resuscitation events, only the first in-hospital CPR was included.

Exclusion criteria

Patients with existing Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order
Patients younger than 65 years old
Out-of-hospital CPR in the index admission
CPR occurred in ICU / Emergency Department / Operating Theatre / wards other than medical wards

Treatment and study plan

cardiopulmonary resuscitation

Procedure

cardiac compression, endotracheal intubation, defibrillation, and use of cardiovascular medications, to restore circulation in patients with cardiac arrest

Primary outcomes

sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year.

Time frame: 2017 - 2018

Sustained ROSC is defined as documented return of adequate circulation in the absence of ongoing chest compressions, and the duration should be of 20 minutes or above

Sponsors and collaborators

Lead sponsor

Jane Yidan Zhu

Other

Registry information

Official study title

A Retrospective Review on Charlson Comorbidity Index (CCI) as a Predictor of Return-of-spontaneous-circulation and Survival-to-discharge of Geriatric In-hospital Cardiopulmonary Resuscitation (CPR) in a Regional Acute Hospital in Hong Kong

Important dates

Study start: 2019
Primary completion: 2019
Study completion: 2019
First posted: Jan 18, 2024
Registry last updated: Jan 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed