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Completed

NCT Number: NCT03254940

Charge: A Text Messaging-based Weight Loss Intervention

This study evaluates different versions of a text messaging-based app for weight loss. This study will place participants to 1 of 32 experimental conditions that reflect different texting components and levels. Participants will be randomized to a condition. The investigators will recruit 448 adults into a 6-month weight loss program, with an additional follow-up 6-months after the intervention ends.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Duke University

Durham, North Carolina, 27708, United States

About this study

Standalone text messaging-based weight loss treatments are scalable and can achieve population reach. However, these interventions are also modular; they can be delivered independently to maximize cost-effectiveness or combined with other approaches (e.g. provider counseling) to maximize outcomes. This study is a 12-month experimental trial among 448 adults with obesity. All participants will receive a core 6-month weight loss texting intervention that includes tailored behavior change goals, interactive self-monitoring, automated feedback, and skills training. Participants will be randomly assigned to 1 of 32 different experimental conditions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • males and females aged 18-65 years
  • participants have English language proficiency
  • participants have a BMI between 25-40 kg/m2
  • Participants will own a smartphone
  • Participants will be willing to receive multiple text messages daily.

Exclusion criteria

  • prior or planned bariatric surgery
  • psychiatric hospitalization in past 12 months
  • pregnancy, nursing, or planned pregnancy
  • history of a cardiovascular event
  • history of an eating disorder
  • history of a condition (e.g., end stage renal disease, cancer, schizophrenia) or use of medications (e.g., lithium, steroids, anti-psychotics) that would affect weight measurement, for which weight loss is contraindicated, or might promote weight change
  • current participation in a weight loss trial and/or recent weight loss > 10%
  • investigator discretion for safety reasons

Treatment and study plan

Charge

Behavioral

Text messaging-based study to determine effect of different components on weight loss.

Primary outcomes

  1. Average Weight Change

    Time frame: baseline, 6 months

    Mean change in weight in kg (6 months post-randomization- baseline weight)

Secondary outcomes

  1. Change in Diet

    Time frame: baseline, 6 months

    To experimentally determine the effects of text messaging components and levels on change in dietary intake using The Rapid Eating Assessment for Participants - Shortened version (REAP-S). The range of score is 13 to 39, where a higher score indicates more healthy dietary intake.

  2. Average Change in Physical Activity

    Time frame: baseline, 6 months

    To experimentally determine the effects of text messaging components and levels on change in weekly minutes of physical activity based on the WHO Global Physical Activity Questionnaire version 2 (GPAC 2). The range of scores is 0 minutes/week to 10,080 minutes/week (maximum number of minutes in a week).

Sponsors and collaborators

Lead sponsor

Duke University

Other

Registry information

Official study title

Charge: Optimizing a Standalone Text Messaging-Based Weight Loss Intervention

Important dates

Study start
2018
Primary completion
2019
Study completion
2023
First posted
Aug 21, 2017
Registry last updated
Apr 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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