Characterization of the Autofluorescence of Healthy and Pathological Tissues of Vocal Cords

The aim of this clinical trial is to provide information about autofluorescence of pathological versus healthy vocal folds tissues.

Experimentations are performed on vocal folds biopsies obtained from patients, surgered at ENT department, university hospital of Besançon. After being extracted, samples of vocal folds are submitted to excitations at 365 nm, 405 nm and 450 nm; light spectral absorptions are measured, and results are compared to reference anatomopathology.

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Key information

Conditions

Laryngeal Neoplasms Head and Neck Neoplasms Laryngeal Diseases Neoplasms Neoplasms by Site Otorhinolaryngologic Diseases Otorhinolaryngologic Neoplasms Respiratory Tract Diseases Respiratory Tract Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHRU de Besancon

Besançon, 25000, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patient view in ENT department, presenting vocal fold lesion that necessitate biopsy
patient informed and with non opposition

Exclusion criteria

small (<1mm) and/or brittle sample
Patients in emergency situations, pregnant or nursing mothers, persons deprived of their liberty, minors or protected adults.

Treatment and study plan

Primary outcomes

hyperspectral fluorescence of vocal folds

Time frame: 30 minutes after biopsy

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Besancon

Other

Registry information

Official study title

Caractérisation de l'Autofluorescence Des Tissus Sains et Pathologiques Des Cordes Vocales

Acronym: FLUOROCORD

Important dates

Study start: 2014
Primary completion: 2014
Study completion: 2016
First posted: Jul 12, 2018
Registry last updated: Jul 12, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed