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Completed

NCT Number: NCT03797638

Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects

Writer's cramp is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non task-relevant fingers. Patients with Writer's cramp also have difficulty in fine control of grip force.

The investigators have recently developed the Finger Force Manipulandum which quantifies the forces applied by each fingers in different tasks. This method is sensitive for detection and quantification of small unwanted contractions in non-active ('stationary') fingers. Different tasks have been developed to assess abilities such as finger individuation but also fine finger force control, finger movement regularity and speed.

The aim of this study is to assess if developed tasks allow to precisely characterize writer's cramp condition in terms of abilities aforementioned.

To do so, performance of 20 writer's cramp patients in the developed task will be compared with performance of 20 control participants (matched in age, sex and writing hand) in the same tasks.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Fondation A de Rothschild

Paris, 75019, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for patients with writer's cramp

  • Patient with writer's cramp and writing speed <140 letters / min
  • Writer's cramp focal dystonia specific to the task of writing
  • Patient treated or not with botulinum toxin injection
  • Person having attended school in French

Non inclusion criteria for patients with writer's cramp

  • Patients whose writer's cramp has no impact on the handwriting and has kept a writing speed> 140 letters per minute.
  • Tremor of writing
  • Neurological condition other than writer's cramp (eg Parkinson's syndrome)
  • Pain, trauma or pathology of the upper limb of the writing member other than the writer's cramp who required medical or surgical treatment in the last 6 months preceding the initial check-up

Inclusion criteria

for control subjects

•> 18 years old

  • Without writer's cramp
  • Person having attended school in French

Non inclusion criteria for control subjects

  • Tremor of writing
  • Neurological condition other than writer's cramp (eg Parkinson's syndrome)
  • Pain, trauma or pathology of the upper limb of the writing member other than the writer's cramp who required medical or surgical treatment in the last 6 months preceding the initial check-up

Matching criteria between cases and control patients

  • Age (± 5 years)
  • Gender
  • Hand writing

Treatment and study plan

Finger Force Manipuladum (FFM)

Device

Tasks performed with the device Finger Force Manipuladum (FFM), to assess abilities such as finger individuation but also fine finger force control, finger movement regularity and speed.

Primary outcomes

  1. Manual dexterity by the FFM

    Time frame: Inclusion

    Compare the manual dexterity by the FFM between subjects with writer's cramp and control subject

Sponsors and collaborators

Lead sponsor

Fondation Ophtalmologique Adolphe de Rothschild

Network

Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

Registry information

Acronym: FFM_CT

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Jan 9, 2019
Registry last updated
Jun 22, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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