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NCT Number: NCT06076005

Characteristics of Advanced LUNG CANCER at the tIme of Diagnosis in a Large Italian Cohor

The distribution of demographic, clinical, radiological, pathological and molecular characteristics of lung cancer at the time of diagnosis, as well as preferential association between elements of those domains, have not been specifically studied in Italy. The aim of the present project is to assess, in a systematic fashion, the demographic, clinical, radiological, pathological and molecular characteristics of advanced lung cancer at the time of diagnosis in a large Italian cohort of consecutive patients referred to two tertiary referral centers.

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Key information

Conditions

Lung Cancer Stage IV Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Interventional Pulmonology Division - Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

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Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age >18 years
  • Suspicion of lung cancer based on imaging (CT and/or PET/CT)
  • Indication to a biopsy for diagnosis, staging and/or molecular profiling

Exclusion criteria

  • Inability or unwillingness to provide a written informed consent
  • ECOG performance status (>3) which makes a tissue diagnosis unfeasible
  • ASA 4 status
  • TNM Stage I-III

Treatment and study plan

Advanced lung cancer patients' group

Other

Evaluation of the demographic, clinical, histological and molecular characteristics of advanced lung cancer at the time of Diagnosis

Primary outcomes

  1. Distribution of histologic subtypes

    Time frame: 24 months

    The investigators will assess the prevalence of histologic subtypes in patients with advanced lung cancer

Secondary outcomes

  1. Distribution of histologic subtypes according to clinical and radiological characteristics

    Time frame: 24 months

    The investigators will assess the prevalence of different histologic subtypes according to clinical and imaging characteristics

  2. Molecular profiling

    Time frame: 24 months

    Prevalence of individual molecular markers in patients with advanced non-squamous non-small cell lung cancer histology

  3. Time to diagnosis

    Time frame: 24 months

    Time lag between onset of symptoms (if any) and invasive testing

Study contacts

Contact information is provided by the study sponsor or research team.

Rocco Trisolini, MD

CONTACT

[email protected]

0630154163

Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Official study title

Demographic, Clinical, Histological and Molecular Characteristics of Advanced LUNG CANCER at the tIme of Diagnosis in a Large Italian Cohort, an Observational Cohort Study: Lung Cancer ID Study

Acronym: LUNG-CANCER

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Oct 10, 2023
Registry last updated
Sep 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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