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NCT Number: NCT06707727

Characteristics and Prognostic Outcomes of Diaphragmatic Ultrasound in Myasthenia Gravis

The goal of this observational study is to learn about the characteristics and prognostic outcomes of diaphragmatic ultrasound in myasthenia gravis. The main question it aims to answer is:

Does diaphragmatic ultrasound predict prognosis of myasthenia gravis in six months? Participants diagnosed as myasthenia gravis will take the diaphragm ultrasound examinations.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Myasthaenia Gravis

Sex eligibility

All sexes

Study type

Observational

Primary location

The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400016, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1: Patients who seek treatment at the First Affiliated Hospital of Chongqing Medical University and have fluctuating skeletal muscle weakness and at least one of the following three conditions will be included: positive reaction to cholinesterase inhibitors

2: Serum positive antibodies against acetylcholine receptors, muscle specific kinases, or lipoprotein related proteins

3: Repeated electrical stimulation examination showed a decrease in wave amplitude.

Exclusion criteria

  • 1: Patients with lung disease or heart failure, or a history of non-invasive ventilator or tracheotomy

Treatment and study plan

Primary outcomes

  1. QMG changes

    Time frame: 6 months

Secondary outcomes

  1. Changes in medication type or dose

    Time frame: 6 months

    acetylcholinesterase inhibitors, glucocorticoid, immunosuppressant

  2. respiratory infection

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

First Affiliated Hospital of Chongqing Medical University

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Nov 27, 2024
Registry last updated
Nov 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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