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OpenTrials
Completed

NCT Number: NCT02535793

Characterisation of Occupational Allergy to Drosophila

Allergy is a very common problem and can be a handicap in everyday life, specially when symptoms occur at work place. Some persons working with drosophila developed respiratory symptoms. Investigators tried to analyze if these manifestations could be due to a specific allergy to drosophila.

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Key information

Age range

18 year–68 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hôpital Arnaud de Villeneuve

Montpellier, 34295, France

About this study

To do so, investigators invited laboratory workers who presented any symptoms in presence of drosophila to undergo skin prick tests in order to determine if a specific sensibilization to drosophila exists. Then, a blood sample is taken from these persons to research specific IgE directed against drosophila. By this way, investigators hope determine if a specific allergy to drosophila exists, its characteristics as prevalence, symptoms, populations concerned...in order to better protect laboratory workers and prevent allergy incidence.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • major males or females (aged <68) who work in laboratory with drosophila in Montpellier (France)
  • clinical symptoms in presence of drosophila
  • The subject must be affiliated to a social security scheme
  • Provision of informed consent prior to any study specific procedures

Exclusion criteria

  • The patient has indicated against (or incompatible drug combination) concerning the implementation of a prick test
  • antihistamine cure in progress
  • Inability to understand the nature and goals of the study and / or communication difficulties with the investigator
  • No affiliation to a French social security recipient or not such a scheme
  • Major protected by law (guardianship, curator or under judicial protection)
  • deprivation of liberty by judicial or administrative decision
  • Increased likelihood of non compliance to the protocol or abandonment under study
  • pregnancy or breastfeeding

Treatment and study plan

blood test (four dry tubes 7ml) and prick tests

Other

Primary outcomes

  1. Number of participants with positive prick test to drosophila

    Time frame: The day of inclusion

    Prick tests : measuring the size of the skin reaction (wheal) after prick tests with drosophila. A wheal measuring more than 4 millimeters in diameter sign a sensitization to drosophila. Then, a blood sample is collected in order to measure specific drosophila IgE rate

Secondary outcomes

  1. Survey to analyse risk factors for allergy to drosophila

    Time frame: The day of inclusion

    analysis of professional (attended institute, time from start working with drosophila, type of animal manipulation (species, living, dead, DNA, protein) use of protection,) or personal factors (age, gender, others allergies, treatment used) which could lead to allergic reaction to drosophila

Sponsors and collaborators

Lead sponsor

University Hospital, Montpellier

Other

Registry information

Acronym: DROSOALLERG

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Aug 31, 2015
Registry last updated
Apr 12, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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