Skip to main content
OpenTrials
Completed

NCT Number: NCT05882383

Changes of Optical Quality During the Peak of the Covid-19 Pandemic

To explore whether cornea structure, and optical quality are affected by the covid-19 infection.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Corneal Wavefront Aberration Corneal Diseases Eye Diseases Refractive Errors SARS-CoV-2

Age range

18 year–32 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tianjin Eye Hospital

Tianjin, Tianjin Municipality, China

About this study

Participants with healthy corneas admitted to Tianjin Eye Hospital from November 25 to January 20, 2022 were followed up . At the end of the follow-up, the investigators recorded in detail whether the patients had undergone real-time reverse transcriptase polymerase chain reaction (covid-19 RT-PCR tests) testing, testing time and results. The presence of PCR-positive during follow-up is considered to be covid-19 infection; PCR-Negative and no symptoms of infection during the follow-up period are considered not infected; participants with symptoms but no PCR test were excluded from the study.Participants were divided into three groups according to the RT-PCR results and the presence or absence of symptoms of infection during follow-up. pentacam (Pentacam HR, Oculus, Wetzlar, Germany) was performed during follow-up and the results were recorded,and the data was statistically managed and compared.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Included Criteria

  • Best corrected visual acuity (BCVA) ≥ 20/20;
  • No other eye diseases except myopia and astigmatism;
  • The cornea was transparent, and there was no cloud or pannus;
  • No clinical manifestation of Eye disease or systemic disease;

Exclusion criteria

  • corneal disease;
  • ocular trauma;
  • Pregnant and lactating women;

Treatment and study plan

Primary outcomes

  1. The value of cornea aberration

    Time frame: 1 months

    The value of aberration data from pentacam during follow-up were compared, including coma, spherical aberration, defocus, and astigmatism

  2. The value of cornea backscatter

    Time frame: 1 months

    The value of cornea backscatter from pentacam during follow-up were compared, including anterior layer，central layer and posterior

  3. The value of cornea thickness

    Time frame: 1 months

    The value of cornea thickness from pentacam during follow-up were compared, includig the thinnest point, apex of the cornea.

Sponsors and collaborators

Lead sponsor

Tianjin Eye Hospital

Other

Registry information

Official study title

Changes of Optical Quality During the Peak of the Covid-19 Pandemic From November 2022 to January 2023 in China

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
May 31, 2023
Registry last updated
May 31, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.