University of Naples "Federico II"
Naples, Italy, 80100
NCT Number: NCT06664515
The notable increase in MPOD following successful surgery suggests its potential role as a valuable adjunctive biomarker associated with a good visual prognosis following this type of macular hole surgical interventions.
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Observational
Naples, Italy, 80100
Full-thickness macular hole (FTMH) is a debilitating retinal disorder, particularly in its advanced forms, necessitating surgical intervention for vision restoration. This study showes the successful closure of a large FTMH using the inverted flap technique, highlighting the essential role of multimodal imaging, and particularly of macular pigment optical density (MPOD) assessment, in preoperative and postoperative evaluation.
Surgery was performed by an expert vitreoretinal surgeon, resulting in significant postoperative improvements in visual acuity and retinal architecture. Multimodal imaging, including MPOD assessment, played a pivotal role in preoperative evaluation and postoperative monitoring.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
age older than 60 years
Exclusion criteria
No diagnosis of pseudophakic cystoid macular oedema
invert flap tecnique
Time frame: 6 months
The parameters analyzed by OCT and MPOD six months after surgery are:
OCT MPOD visual acuity
Time frame: six months
The parameters analyzed six months after surgery are:
MPOD Visual acuity OCT
Federico II University
Other
Changes in Macular Pigment Optical Density After Full-thickness Macular Hole Closure Using Inverted Flap Technique
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