Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears

The hypothesis is that the measured tear osmolarity from study participants decrease with sustained use of a over-the-counter artificial tears, TheraTears® lubricating drops, over an eight week period. Participant's dry eye symptoms would also improve with sustained use of TheraTears® lubricating drops.

Inclusion criteria

• Is at least 21 years of age and has full legal capacity to volunteer;
• Has read and signed the information consent letter;
• Is willing and able to follow instructions and maintain the appointment schedule;
• Is diagnosed with dry eye syndrome (in at least one eye), indicated by current ocular examination, prior history (self-reported history of dry eye is acceptable) and current use of treatments for dry eye;
• Has a minimum osmolarity reading of 316 mosm/kg at the baseline visit in at least one eye.

Exclusion criteria

• Has taken part in another research study within the last 30 days;
• Planned contact lens wear during the course of the study;
• Staff at the investigational site or family member of site staff or family member of currently enrolled participant;
• Any subject that violates the washout period by using eye drops during the 72hrs washout period;
• Has any known ocular disease including active ocular infection, inflammation or allergy, especially Salzmann's nodular degeneration, symptomatic conjunctivochalasis, and fixation disparity syndrome;
• Used Restasis (or similar topical medication) within the last 6 months;
• Has a systemic condition that in the opinion of the investigator may affect the dry eye status of the subject, especially those newly diagnosed, newly prescribed and/or unstable;
• Is pregnant, lactating or planning a pregnancy at the time of enrolment (verbal confirmation necessary);
• Use of medications such as: Systemic Antihistamine (e.g., Allegra®, Benadryl®, Claritin®, Dimetapp®, Unisom®, Zyrtec®, etc.), Isotretinoin (e.g., Accutane®, Roaccutane®, Amnesteem®, Claravis®, Isotroin®, Sotret®) or similar medications;
• Has known sensitivity to the diagnostic pharmaceuticals to be used in the study;
• Has undergone ocular surgery(LASIK, Cataract, etc)within the last year.