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OpenTrials
Completed

NCT Number: NCT00308490

Changes in Iron Markers Following Iron Loading in Hemodialysis Patients

The purpose of this study is to describe alterations of serum ferritin, transferrin saturation, soluble transferrin receptor, % hypochromic erythrocytes, % reticulocytes, reticulocyte hemoglobin content after iron loading in hemodialysis patients.

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Key information

Conditions

Anemia in Chronic Renal Disease

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Papageorgiou General Hospital

Thessaloniki, 56429, Greece

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • hemodialysis for three months minimum
  • stable epoetin dose for two months minimum
  • serum ferritin concentration < 1000 ng/ml
  • transferrin saturation < 50%
  • parathormone concentration < 800 pg/ml

Exclusion criteria

  • hemoglobin concentration > 13g/dl
  • serum ferritin concentration < 20 ng/ml
  • vitamin B12 and/or folic deficiency
  • other hematologic disease than anemia
  • cancer
  • hypothyroidism
  • infectious disease

Treatment and study plan

Iron sucrose

Drug

Primary outcomes

  1. Ferritin alterations after iron loading at six and twelve weeks from the beginning of iron loading.

Secondary outcomes

  1. All iron indices' alterations during twelve weeks from the beginning of iron loading.

Sponsors and collaborators

Lead sponsor

Papageorgiou General Hospital

Other

Registry information

Official study title

Phase IV Study of Iron Indices' Kinetics in Hemodialysis Patients

Important dates

Study start
2005
Study completion
2007
First posted
Mar 29, 2006
Registry last updated
Mar 13, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.