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OpenTrials
Completed

NCT Number: NCT03867422

Changes in Brain Tissue Pulsatility With Musical Stimuli

Music Perception is well known to elicit emotions and neuronal activations. Changes in the cerebrovascular physiology have also been found in emotional tasks but only few studies have investigated markers of cerebrovascular physiology in a music task and no study has used the Ultrasound method of Tissue Pulsatility Imaging (TPI) in a music task. The use of TPI to measure reactivity of Brain Tissue Pulsatility Imaging (BTP) could further elucidate the cerebral basis of music perception.

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Key information

Conditions

Healthy

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Observational

Primary location

DESMIDT

Tours, 37044, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • more or equal 18 years-old and less or equal 45 years-old
  • no known hearing problem

Exclusion criteria

  • professional musician
  • history of neurologic, psychiatric or cadiologic disease
  • treatment which could impact parameters of brain tissue pulsatility and peripheral nervous system
  • opposition to use the data

Treatment and study plan

Primary outcomes

  1. amplitude of variations in brain tissue pulsatility

    Time frame: Baseline

    in micrometers

Secondary outcomes

  1. heart rate

    Time frame: Baseline

    beat by minute

  2. breathing rate

    Time frame: Baseline

    Frequency

  3. skin conductance

    Time frame: Baseline

    in milliVolt

  4. score of barcelona music reward questionnary (BMQR)

    Time frame: Baseline

    BMQR: Barcellona Music Reward Questionnaire for the evaluation of musical anhedonia;

    • Only the total score of musical reward will be reported; for total score, minimum value is 20, maximum value is 100. Values under 40 represent low values in the overall score; values above 60 indicate high values in the overall score;
    • High global score (>60) represents a better outcome; low global score (<40) represents a worse outcome, notably an impairment in music reward processing;
    • The overall score is computed by adding raw scores of the items (except for items 2 and 5, which need to be reversed).

Sponsors and collaborators

Lead sponsor

University Hospital, Tours

Other

Registry information

Acronym: M-PULSE

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Mar 8, 2019
Registry last updated
Aug 21, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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