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OpenTrials
Completed

NCT Number: NCT03870139

Cerebral and Peripheral Electrical Stimulation on Isometric Quadriceps Strength

Quadriceps muscle strength is a key goal to be achieved in rehabilitation protocols for a variety of musculoskeletal conditions. Both cerebral and peripheral electrical stimulations can modulate motor brain areas involved in motor functions and has the potential to optimize muscle capacity. However, their effects on quadriceps function are lacking.

This study aims to investigate the effects of transcranial direct current stimulation (tDCS) and peripheral electrical stimulation (PES) on quadriceps strength in healthy subjects.

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Key information

Conditions

Healthy Volunteers

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Department of Physical Therapy. Federal University of Piaui

Parnaíba, Piauí, 64202020, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects with no complaints of pain, discomfort in the musculoskeletal system.

Exclusion criteria

  • Musculoskeletal or neurological disorder
  • Under medication

Treatment and study plan

Cerebral stimulation

Device

Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation (NIBS) technique that has been investigated for the management of various health conditions. However, its ergogenic effect still has controversial results.

Other names: Transcranial direct current stimulation

Peripheral stimulation

Device

Peripheral electrical stimulation (PES) activates a complex neural network involving a series of neurotransmitters and receptors capable of promoting segmental and extrasegmental analgesia. Moreover, recent evidence has shown that PES can activate brain motor areas such as primary motor cortex.

Primary outcomes

  1. Isometric quadriceps strength

    Time frame: Pre and Post-test (immediately after tDCS)

    Maximal isometric voluntary contraction (Kgf)

Secondary outcomes

  1. Isometric quadriceps strength

    Time frame: During stimulation

    Maximal isometric voluntary contraction (Kgf)

  2. Isometric quadriceps strength

    Time frame: 10 minutes post-stimulation

    Maximal isometric voluntary contraction (Kgf)

Sponsors and collaborators

Lead sponsor

Universidade Federal do Piauí

Other

Registry information

Official study title

Effects of Peripheral and Cerebral Electrical Stimulation on Maximal Isometric Strength of Knee Extensors

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Mar 11, 2019
Registry last updated
May 9, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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