Thorsten of Rudroff
Iowa City, Iowa, 52240, United States
NCT Number: NCT04760899
This study is investigating the immediate and long-term effects of bilateral cerebellar transcranial direct current stimulation on cognition, balance, and symptom severity in people with sports-related post-concussion syndrome. The central hypothesis is that tDCS will provide improvements in cognitive deficits, balance, and overall symptom attenuation in people with SRPCS both acutely and at 2 and 4 week follow ups. The researchers further hypothesize that cerebellar tDCS will ameliorate the symptoms of people with SRPCS.
This study is active but is not currently recruiting participants.
18 year–30 year
All sexes
Interventional
Not applicable
Iowa City, Iowa, 52240, United States
The long term goal is to develop an effective and broadly applicable treatment modality for athletes who develop SPRCS. The objective of this study is to investigate the effects of multiple (5 consecutive daily) sessions of 2 milliampere (mA) right cerebellar tDCS on cognitive deficits, balance, and overall attenuation of symptoms on people with SRPCS. Cognitive deficits will be assessed with the N-back Working Memory test, list sorting test, and dimensional change card test. Balance deficits will be assessed with the Berg Balance Scale and Standing Balance Test (SBT), and symptoms will be assessed via the Rivermead Post-Concussion Symptom Questionnaire (RPQ). The cognitive and balance tasks are taken from the NIH motor toolbox and have been shown to be the most important for health and success in school and work, and the RPQ is one of the most widely used SRPCS evaluation tools. The central hypothesis is that tDCS will provide improvements in cognitive deficits, balance, and overall symptom attenuation in people with SRPCS both acutely and at 2 and 4 week follow ups. The researchers further hypothesize that cerebellar tDCS will ameliorate the symptoms of people with SRPCS. The rationale is that the results will improve the quality of life of these patients and may prevent impairment of cognitive function later in life.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Healthy Controls
Exclusion criteria
Transcranial Direct Current Stimulation is a form of non-invasive brain stimulation. It uses small electrodes to deliver small amounts of current to specific areas of the brain to either increase or decrease excitability.
Other names: tDCS
Time frame: 2 weeks
Balance Assessment. This is a 14 item test with scores from 0 to 4, with 4 being no inhibition at all. The max score on this test is 56, higher scores indicating better balance.
Time frame: 2 weeks
Balance Assessment. Outcomes of this test are overall postural sway translated into a normalized t-score.
Time frame: 2 weeks
Assessment of Cognition/
Time frame: 2 weeks
Assessment of Cognition
Time frame: 2 weeks
Assessment of Cognition
Time frame: 2 and 4 week follow ups
Assessment of Cognition
Time frame: 2 and 4 week follow ups
Balance Assessment. This is a 14 item test with scores from 0 to 4, with 4 being no inhibition at all. The max score on this test is 56, higher scores indicating better balance.
Time frame: 2 and 4 week follow ups
Balance Assessment. Outcomes of this test are overall postural sway translated into a normalized t-score.
Time frame: 2 and 4 week follow ups
Assessment of Cognition
Time frame: 2 and 4 week follow ups
Assessment of Cognition
University of Iowa
Other
Bilateral Cerebellar Transcranial Direct Current Stimulation (tDCS) for the Treatment of Sports-Related Post-Concussion Syndrome (SRPCS)
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