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OpenTrials
Completed

NCT Number: NCT00947726

Ceramide Containing Multivesicular Emulsion Application . . .

We believe that using a ceramide based foot cream two times a day for two weeks will prevent water loss and overall foot dryness in patients with non-insulin dependent diabetes.

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Key information

Conditions

Foot Transepidermal Water Loss in Patients in NIDDM Foot Dryness in Patients With NIDDM

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • >18 years of age
  • non insulin-dependent diabetes
  • moderate to severe xerosis of both feet [a score of at least 4 on a scale of 0 (normal) to 8 (deep fissuring)]
  • capable of understanding and signing consent form

Exclusion criteria

  • history of ichthyosis vulgaris
  • known hypersensitivity to the topical product used in the study
  • previous use of high potency steroids (class I and II) in past 2 week
  • presence of acute skin disease or infection, such as vasculitis or cellulitis
  • presence of foot ulcer
  • evidence of gangrene

Treatment and study plan

CeraVe

Other

Using over the counter (OTC) cream on foot twice daily for two weeks.

Other names: Ceramide based foot cream

Primary outcomes

  1. Decrease transepidermal water loss and foot dryness in study subjects.

    Time frame: Baseline and 5 weeks

Sponsors and collaborators

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Nih

Collaborators

  • The University of Texas Health Science Center, Houston

Registry information

Official study title

Ceramide Containing Multivesicular Emulsion Application as a Skin Hydration Treatment for Feet of Subjects With Non-insulin Dependent Diabetes Mellitus.

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Jul 28, 2009
Registry last updated
Feb 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.