Skip to main content
OpenTrials
Completed

NCT Number: NCT01431235

CBT for Patients With Attention Deficit Hyperactivity Disorder (ADHD) and Substance Use Disorders

The purpose of this study is to determine if cognitive behavioral therapy is effective in treating ADHD symptoms in patients with substance use disorders and comorbid ADHD.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Attention Deficit Hyperactivity Disorder Attention Deficit Disorder with Hyperactivity Attention Deficit and Disruptive Behavior Disorders Chemically-Induced Disorders Mental Disorders Neurodevelopmental Disorders Substance Use Disorders Substance-Related Disorders

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Arkin

Amsterdam, Netherlands

About this study

Attention Deficit Hyperactivity Disorder(ADHD) is an important comorbid condition in patients with substance use disorders (SUD). The prevalence of ADHD in patients with SUD is estimated 23%, and ADHD is associated with an untoward prognosis of SUD. However, adequate treatment programs for patients with ADHD and SUD are not available. Results of medication trials for patients with ADHD and SUD are disappointing, and cognitive behavioral therapy (CBT) has not yet been investigated in this population. In patients with ADHD without comorbid SUD, the results of CBT in randomized trials are positive. The purpose of this study is to investigate if CBT is effective in treating ADHD symptoms in patients with ADHD and SUD.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • substance use disorder
  • ADHD
  • able to comply with study activities

Exclusion criteria

  • severe neurological or psychiatric diseases (for example Parkinson, dementia, psychosis, bipolar depression) which require medication
  • unable to read or write Dutch language

Treatment and study plan

cognitive behavioral therapy for treating ADHD symptoms

Behavioral

5 sessions of one hour CBT for treating ADHD symptoms by a trained health care worker

Primary outcomes

  1. self reported ADHD symptoms

    Time frame: 6 months

    Dutch self report list of ADHD symptoms by Kooij and Buitelaar

Secondary outcomes

  1. Time Line Follow Back method

    Time frame: 6 months

    self-reported alcohol and drug use

  2. Beck depression inventory

    Time frame: 6 months

    self reported depression symptoms

  3. Beck Anxiety Inventory

    Time frame: 6 months

    Self reported anxiety symptoms

  4. EQ-5

    Time frame: 6 months

    Self reported quality of living

  5. TIC-P

    Time frame: 6 months

    health care consumption and production loss in relation to mental health problems

  6. Stroop task

    Time frame: 6 months

    neuropsychological measure

  7. Tower of London task

    Time frame: 6 months

    neuropsychological task

  8. BART task

    Time frame: 6 months

    neuropsychological task on risk taking behavior

  9. urine checks

    Time frame: 6 months

    urine checks on drug use

Sponsors and collaborators

Lead sponsor

Arkin

Industry

Collaborators

  • Fonds NutsOhra

Registry information

Official study title

Investigating the Efficacy of Cognitive Behavioral Therapy in Patients With Substance Use Disorder and Comorbid ADHD. A Randomized Controlled Trial With Cognitive Behavioral Therapy

Important dates

Study start
2011
Primary completion
2016
Study completion
2016
First posted
Sep 9, 2011
Registry last updated
Jan 16, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.