Cause and Consequence of Neural Fatigue

Inclusion criteria

• Right-handed people;
• between 20 à 39 years old;
• able to understand the instructions and to perform the behavioral tasks of the study ;
• informed consent to take part to the study (signature of a a consent form);
• people being registered to social security or universal medical protection or equivalent;

Exclusion criteria

For each experiment:

• neurological, psychiatric or serious illness history
• ongoing or recently stopped (lower than three weeks) psychotropic treatment;
• excessive psychotropic substances consumption or chronical consumption the examination day;
• People being not able to perform the tasks (alteration of one of the cognitive functions or elementary visual disorder avoiding the identification of the experimental stimuli);
• adult under legal protection (guardianship, or under the protection of a conservator);
• adult people being not able to express his consent;
• people being deprived of liberty as a consequence of an administrative or judicial decision;
• pregnant, parturient or nursing women;
• people taking part to another biomedical study or still being in the exclusion phase of another research;
• hospitalized people without consent;
• people who could not participate to the full study for any reasons.

For the experiments involving transcranial stimulation, in addition to the previous ones:

• take of drugs known to lower the epileptogenic threshold;
• take of barbiturate, gabapentin, topiramate, clonazepam in the 7 days before the first visit;
• history of awareness loss;
• people having contraindication for having a transcranial magnetic stimulation or for having an MRI examination;
• People who does not want to be informed of any significant irregularity that could be detected during the MRI examination;
• claustrophobic people ;