Cataract Surgery vs Cataract Surgery With ECPL for Treatment of Plateau Iris Configuration or Syndrome

Inclusion criteria

• Patient has to be ≥ 18 years of age of either gender
• Nuclear sclerotic cataract graded by LOCS III to be < 5
• Diagnosis of Plateau Iris Configuration or Syndrome
• No contraindication for cataract or ECPL operation
• Written informed consent on IRB approved Informed Consent Form

Exclusion criteria

• Hard cataracts, LOCS III 5 and 6
• Ciliary body cysts
• Clinically significant sequelae from trauma in which angle anatomy/physiology may have been compromised (e.g., chemical burns, significant angle recession, blunt trauma, etc.)
• Congenital anomaly of the irido-trabecular angle
• Previous intraocular surgery
• Previous laser gonioplasty to either eye
• Placement of the intraocular lens in any place other than the capsular bag
• Pupilloplasty
• Rubeosis
• Peripheral anterior synechiae (PAS) nasal angle and/or >180 degrees of PAS
• Neovascular glaucoma; or glaucoma associated with vascular ischemic disorders
• Active corneal inflammation or edema (e.g., keratitis, keratoconjunctivitis, keratouveitis)
• Corneal opacities or disorders that would inhibit visualization of the nasal angle
• Chronic ocular inflammatory disease or presence of active ocular inflammation with risk for synechial/proliferative changes
• Inability to attend regular follow-up assessment or to give informed written consent.