Case-Control Study to Identify Risk Factors for Microscopic Colitis

The purpose of the study is to assess among others environmental and hygiene-related risk factors for microscopic colitis (MC), a common diarrheal disease.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Microscopic Colitis Colitis Colitis, Collagenous Colitis, Lymphocytic Colitis, Microscopic Collagenous Colitis Colonic Diseases Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Intestinal Diseases Lymphocytic Colitis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Maastricht UMC

Maastricht, Limburg, Netherlands

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Confirmed Diagnosis of MC (CC or LC) between January 1, 2000 and December 31, 2012.
Inhabitant of the province of Limburg or the Eindhoven region at the moment of diagnosis

Exclusion criteria

Below 18 years of age at the time of diagnosis
Not capable of signing an informed consent
Deceased at moment of approximation

Treatment and study plan

Whole saliva sample

Other

Both case and control group will be approached to consider to give permission to sample saliva. This is not obligatory. Collected samples will be stored for future DNA research.

Primary outcomes

Assessment of environmental and hygiene-related risk factors for microscopic colitis

Time frame: Retrospective, between 2000 and 2012

Information about environmental and hygiene-related risk factors is obtained by a questionnaire, sent to subjects diagnosed with MC between 2000 and 2012

Secondary outcomes

The difference between the CC and LC subpopulation regarding environmental, hygiene-related, and generally known risk factors

Time frame: Retrospective between 2000 and 2012

As generally known risk factors are considered: age, gender, medication, comorbidities and smoking.

Information about risk factors is obtained by a questionnaire, sent to subjects diagnosed with MC between 2000 and 2012.

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

Risk Factors for Microscopic Colitis: A Dutch Case-Control Study

Important dates

Study start: 2014
Primary completion: 2016
Study completion: 2016
First posted: Aug 27, 2013
Registry last updated: Jul 19, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed