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NCT Number: NCT07670559

Carrot Technique Versus Guided Bone Regeneration for Horizontal Ridge Deficiency in the Maxillary Esthetic Zone

This randomized controlled clinical trial aims to compare the effectiveness of the Carrot Technique and Guided Bone Regeneration (GBR) for the management of horizontal alveolar ridge deficiency in patients requiring implant placement in the maxillary esthetic zone. Twenty patients will be randomly allocated into two equal groups. Clinical outcomes including implant stability and soft tissue healing, as well as radiographic outcomes including alveolar ridge width, bone density, and marginal bone loss, will be evaluated using clinical examinations and cone beam computed tomography (CBCT) during a 12-month follow-up period..

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This study is active but is not currently recruiting participants.

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistry, Mansoura University, Al Mansurah, Dakahlia Governorate, Egypt

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About this study

The Carrot Technique is a minimally invasive approach that utilizes an autogenous bone core harvested during implant osteotomy and repositioned to augment the deficient buccal ridge. This technique may reduce donor-site morbidity while providing sufficient horizontal bone augmentation. Guided Bone Regeneration remains one of the most widely used techniques for horizontal ridge reconstruction through the use of bone substitute materials and barrier membranes.

This randomized controlled clinical trial will compare the clinical and radiographic outcomes of the Carrot Technique and GBR in patients presenting with horizontal ridge deficiency in the maxillary esthetic zone. Twenty patients requiring single-tooth implant rehabilitation will be randomly allocated into two equal groups. Group I will receive implant placement combined with the Carrot Technique, while Group II will receive implant placement combined with Guided Bone Regeneration.

Clinical evaluations will include implant stability assessed by resonance frequency analysis, soft tissue healing using the Landry Healing Index, and peri-implant inflammation using the modified sulcus bleeding index. Radiographic evaluation will be performed using cone beam computed tomography immediately after surgery and at 6 and 12 months postoperatively to assess changes in alveolar ridge width, bone density, and marginal bone loss. The study aims to determine whether the Carrot Technique provides comparable or superior outcomes to GBR for horizontal ridge augmentation associated with implant placement.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 to 45 years. Missing a single tooth in the maxillary esthetic zone requiring implant placement.

Good oral hygiene and patient compliance. Medically free from systemic diseases that contraindicate implant surgery. Slight to moderate horizontal alveolar ridge deficiency with a minimum ridge width of 5 mm.

Adequate vertical bone height for implant placement. Medium to hard bone quality (D2-D3 according to Misch classification). Absence of bruxism or other parafunctional habits.

Exclusion criteria

  • Presence of local pathological lesions (e.g., cysts or tumors) at the planned surgical site.

Poor bone quality (D4 bone). Pregnancy. Heavy smoking. Any medical condition contraindicating implant surgery.

Treatment and study plan

Carrot Technique

Procedure

Implant placement with simultaneous horizontal ridge augmentation using an autogenous bone core harvested from the implant osteotomy site with a trephine drill and fixed buccally using osteosynthesis screws.

Guided bone regeneration

Procedure

Implant placement with simultaneous horizontal ridge augmentation using bone substitute material and a collagen membrane according to guided bone regeneration principles.

Primary outcomes

  1. Change in Alveolar Ridge Width

    Time frame: baseline and 12 Months

    Horizontal alveolar ridge width measured using cone beam computed tomography (CBCT). Changes in ridge width will be calculated by comparing measurements obtained immediately after surgery and at follow-up.

Secondary outcomes

  1. Marginal Bone Loss

    Time frame: 12 Months

    Marginal bone loss measured radiographically using CBCT using the implant as a reference.

  2. Soft Tissue Healing

    Time frame: 1 Week, 2 Weeks, and 1 Month

    Soft tissue healing assessed using the Landry Healing Index.

  3. Modified Sulcus Bleeding Index

    Time frame: 1 Month and 12 Months

    Peri-implant soft tissue inflammation assessed using the Modified Sulcus Bleeding Index (mBI).

  4. Bone Density

    Time frame: 12 Months

    Buccal peri-implant bone density measured using CBCT and expressed in Hounsfield Units.

  5. Implant Stability Quotient (ISQ)

    Time frame: At implant placement and 12 months

    Implant stability assessed using resonance frequency analysis and expressed as Implant Stability Quotient (ISQ).

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Evaluation of the Carrot Technique With Simultaneous Implant Placement for Horizontal Alveolar Ridge Deficiency in the Maxillary Aesthetic Zone: A Randomized Controlled Clinical Trial.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 26, 2026
Registry last updated
Jun 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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