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NCT Number: NCT06562049

Carpal Bone Erosion in Rheumatoid Arthritis :Diagnostic Value

Rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by proliferative hyper vascularized synovitis which primarily affects synovial joints. Synovium of bursa; tendon sheaths; attachment sites of cartilage, ligament, and tendons to the bone; soft tissue; and bones can be mentioned among the other areas under influence of RA. Changes happen to be symmetrical and may present as fusiform soft tissue swelling, regional osteoporosis, marginal-central erosions, cartilage damage, joint destruction, narrowing of joint space and fibrous ankyloses. Wrist, metacarpophalangeal and metatarsophalangeal joints are the first sites to be affected .Over the past few years, an increasing number of rheumatologists have started to use US in the clinical setting of the early arthritis clinic. While US allows for an accurate and non-invasive multisite assessment of joint involvement in patients with RA, time for US examination is not infinite

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag University hospitals

Sohag, Egypt

Location contact

Magdy Amin, Professor

CONTACT

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.[8] 2. SLE patients fulfilled the 2019 ACR\\EULAR classification criteria for SLE.[9] 3. Age above 18 years old. 4. Patient cooperative and can answer questions. 5. Patients who are able and willing to give written informed consent.

Exclusion criteria

  • 1. Age below 18 years and above 60 years. 2. Uncooperative patients. 3. Patient not able and willing to give written informed consent.

Treatment and study plan

musculoskeletal ultrasound

Radiation

musculoskeletal ultrasound on both hands

Primary outcomes

  1. bone erosion

    Time frame: max 1 year

    erosions in carpal bones and MCP 2,5 in both hands

Study contacts

Contact information is provided by the study sponsor or research team.

abeer A abdelaal, Resident

CONTACT

[email protected]

01206290115

ahmed M mahrous, Professor

CONTACT

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 20, 2024
Registry last updated
Aug 20, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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