Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07558239

Carotid Intima-media Thickness in Dialysis Patients and Traditional Risk Factors

* Cardiovascular disease (CVD) is the leading cause of mortality in hemodialysis (HD) patients. * Carotid intima-media thickness (CIMT) is a validated surrogate marker for atherosclerosis. * Both traditional cardiovascular risk factors (hypertension, diabetes, dyslipidemia) and dialysis-specific factors (mineral metabolism disorders, dialysis duration) contribute to vascular damage.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Dialysis Patients Arterial Occlusive Diseases Arteriosclerosis Atherosclerosis Cardiovascular Diseases Hypertension Vascular Diseases

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

About this study

  • Cardiovascular disease (CVD) is the leading cause of mortality in hemodialysis (HD) patients.
  • Carotid intima-media thickness (CIMT) is a validated surrogate marker for atherosclerosis.
  • Both traditional cardiovascular risk factors (hypertension, diabetes, dyslipidemia) and dialysis-specific factors (mineral metabolism disorders, dialysis duration) contribute to vascular damage.
  • Gap in knowledge: Few studies have comprehensively assessed the combined impact of these factors on CIMT in HD patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Age 18 or older. 2. Patients with sepsis without AKI at the time of admission.

Exclusion criteria

  • o Active malignancy
  • Acute infections
  • Recent cardiovascular events (<3 months)
  • Poor echocardiographic window for CIMT measurement

Treatment and study plan

Ultrasound measurements of carotid intima- media thickness

Other

Ultrasound measurements of carotid intima- media thickness

Primary outcomes

  1. • To determine the association between carotid intima - media thickness and: o Hypertension duration o HbA1c o LDL/HDL ratio o Dialysis duration o Parathyroid hormone (PTH) levels

    Time frame: 6 month

Secondary outcomes

  1. • To compare CIMT between: o Diabetics vs. non-diabetics o Short (<5 yrs) vs. long (≥5 yrs) dialysis duration o Patients with vs. without hyperparathyroidism (PTH >300 pg/m

    Time frame: 6month

Sponsors and collaborators

Lead sponsor

Minia University

Other

Registry information

Official study title

Association of Traditional Cardiovascular and Dialysis-Specific Risk Factors With Carotid Intima-Media Thickness in Hemodialysis Patients: A Cross-Sectional Study"

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 30, 2026
Registry last updated
Apr 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.