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OpenTrials
Completed

NCT Number: NCT02989376

Carotid Duplex Ultrasound for Selecting Patients for Endovascular Thrombectomy in Acute Stroke Patients

The aim of this study is to address the usefulness of carotid duplex ultrasound as vascular imaging for selecting acute stroke patients for endovascular thrombectomy.

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Key information

Conditions

Stroke, Acute Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Stroke Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kohnan hospital

Sendai, Miyagi, 9828523, Japan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Endovascular treatment can be initiated within 6 hours of symptom onset.
  • ASPECTS of >=6 is diagnosed by two or more stroke physicians.
  • The end diastolic velocity in the common carotid arteries or internal carotid artery is evaluated by carotid duplex ultrasound
  • NIHSS score of >=6.
  • Age>=18 years.
  • Written informed consent is obtained.

Exclusion criteria

  • Pre-stroke modified Rankin Scale (mRS) score >=2.
  • Difficulties to evaluate ASPECTS on initial CT.
  • Difficulties to groin puncture.
  • History of severe allergic reaction to contrast medium.
  • End stage renal disease.

Treatment and study plan

After detection of occluded vessels by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment.

Procedure

When the ratio of the end diastolic velocity in the common carotid arteries is greater than 1.4 or the diastolic flow in the internal carotid artery is not detected by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment. If vessel occlusion is not detected by carotid duplex ultrasound, additional vascular imaging including MR angiography or CT angiography is considered.

Primary outcomes

  1. modified Rankin Scale

    Time frame: at 90 days after onset

Sponsors and collaborators

Lead sponsor

Ryo Itabashi

Other

Registry information

Official study title

Emergent Carotid Ultrasound in Hyperacute Cerebral Vessel Occlusion for Selecting Patients to be Treated With Endovascular Clot Retrieval Treatment

Acronym: ECHO-SELECT

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Dec 12, 2016
Registry last updated
Feb 20, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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