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Completed

NCT Number: NCT06576960

Caries Inhibitory Effect of Nano Silver and Tri Calcium Phosphate Varnishes Among Visually Impaired Children

Assessment of pH,streptococcus mutants count, lactobacillus count and immunoglobulin A among visually impaired children after nano silver varnish application it tri calcium phosphate phosphate varnish application

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Key information

Conditions

Dental Caries Stomatognathic Diseases Tooth Demineralization Tooth Diseases

Age range

8 year–12 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of dentistry

Tanta, Tanta City, 31527, Egypt

About this study

Sixty children will be randomly divided into three equal treatment groups, composed of 20 children each, according to the type of material used as follows:

  • Group I: children will receive oral health education and nano silver fluoride varnish.
  • Group II: children will receive oral health education and tri calcium phosphate varnish.
  • Group III: children will receive oral health education

for all children ,Assessment of pH, streptococcus mutants count, lactobacillus count and immunoglobulin A will be assessed at baseline, one day , 3 months and 6 months after application

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Visually impaired children

Exclusion criteria

  • uncooperative children or children not willing to participate in the study.
  • Children with systemic diseases
  • Children with bronchial asthma.
  • Children who were on antibiotic or medications that might affect oral flora or salivary flow taken within the previous 3 months
  • History of fluoride treatment in the past 3-4 weeks.

Treatment and study plan

Nano silver fluoride varnish and tri calcium phosphate varnish

Drug

Fluoride varnishes

Other names: health education

Primary outcomes

  1. Salivary PH

    Time frame: 6 months

    Salivary power of hydrogen at baseline, one month, 3months and six months after intervention

  2. Salivary streptococcus mutants count

    Time frame: 6months

    Count of bacteria at baseline, one day, 3months and six months after intervention

  3. Lactobacillus count

    Time frame: 6 months

    Count of bacteria at baseline, one day, 3months and six months after intervention

  4. Immunoglobulin A

    Time frame: 6months

    Level of immunoglobulin A at saliva at baseline, one day, 3months and 6 months after intervention

Sponsors and collaborators

Lead sponsor

Hadeer Mohammed Abd El wahab

Other

Collaborators

  • Tanta University

Registry information

Official study title

Caries Inhibitory Effect of Nano Silver Varnish Versus Tri Calcium Phosphate Varnish Among Children With Visual Impairment

Acronym: Prevention

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Aug 29, 2024
Registry last updated
Aug 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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