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Completed

NCT Number: NCT06992167

Caregiver Depression in a Low-Resource Setting: Socio-Demographic Predictors of Major Depressive Disorder Among Family Caregivers of Breast Cancer Patients in Pakistan

This cross-sectional study aims to assess the prevalence of depression among primary caregivers of breast cancer patients within low-resource country like Pakistan. Caregiving for individuals with breast cancer can be physically and emotionally demanding, often leading to psychological distress, including depression. However, there is limited data from low- and middle-income countries, including Pakistan, where caregivers may face additional socioeconomic and systemic burdens. This study seeks to quantify the burden of depression in this population and explore associated sociodemographic and caregiving-related factors. Findings will help inform psychosocial support strategies and interventions to improve caregiver well-being in resource-constrained environments.

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Key information

Conditions

Major Depressive Disorder (MDD) Depressive Disorder Depressive Disorder, Major Mental Disorders Mood Disorders

Age range

15 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ayub Teaching Hospital, Abbottabad, Pubjab, Pakistan

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Primary caregiver of a patient diagnosed with breast cancer at any stage
  • Male or female caregiver
  • Aged 15 years or older
  • Providing physical, emotional, or financial support to the patient
  • Willing to give informed consent

Exclusion criteria

  • Paid caregivers (professional or hired help)
  • Age under 15 years
  • Unwilling to provide consent or participate in the study
  • Incomplete or missing essential data required for analysis

Treatment and study plan

Primary outcomes

  1. Prevalence of depression among caregivers of breast cancer patients

    Time frame: At a single time point during caregiver recruitment (cross-sectional assessment within 6 months of study initiation)

    Depression will be assessed using the Patient Health Questionnaire-9 (PHQ-9), a validated screening tool. The PHQ-9 consists of 9 items, each scored from 0 (not at all) to 3 (nearly every day), for a total score range of 0 to 27. Higher scores indicate worse depressive symptoms. Depression severity will be categorized as follows:

    0-4: Minimal

    5-9: Mild

    10-14: Moderate

    15-19: Moderately Severe

    20-27: Severe

    The proportion of caregivers falling into each category will be reported.

Sponsors and collaborators

Lead sponsor

Rahmah Health Foundation

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
May 28, 2025
Registry last updated
May 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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