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OpenTrials
Completed

NCT Number: NCT04970199

Cardiovascular Protective Role of Laser Acupuncture in Systemic Lupus

Systemic lupus erythematosus is a chronic and multisystemic autoimmune disorder which predominantly affecting women. The most common cause of death in lupus patients affected by disease for more than 5 years is cardiovascular disease due to presence of some factors as oxidative stress, pro-inflammatory cytokines , dyslipidemia, diabetes, and hypertension.

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Key information

Conditions

System; Lupus Erythematosus Autoimmune Diseases Connective Tissue Diseases Immune System Diseases Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases

Age range

18 year–47 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Physical Therapy Cairo University

Giza, Dokki, Egypt

About this study

laser acupuncture (active or sham) for one month (3 days/week ) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian (laser will be applied for 1 min on every acupiont) in lupus females

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • lupus females
  • 60 patients

Exclusion criteria

  • pregnancy
  • cardiovascular diseases
  • respiratory diseases

Treatment and study plan

laser application on acupoints

Device

laser acupuncture

Primary outcomes

  1. Malondialdehyde

    Time frame: It was measured after 4 weeks

    anti-oxidative stress factor

Secondary outcomes

  1. systole

    Time frame: It was measured after 4 weeks

    blood pressure

  2. diastole

    Time frame: It was measured after 4 weeks

    blood pressure

  3. blood glucose

    Time frame: It was be measured after 4 weeks

    fasting

  4. erythrocyte sedimentation rate (1 hour)

    Time frame: It was measured after 4 weeks

    inflammatory marker

  5. erythrocyte sedimentation rate (2 hour)

    Time frame: It was measured after 4 weeks

    inflammatory marker

  6. c reactive protein

    Time frame: It was measured after 4 weeks

    inflammatory marker

  7. adenosine triphosphate

    Time frame: It was measured after 4 weeks

    energy production marker

  8. Nitrate

    Time frame: It was measured after 4 weeks

    oxidative stress factor

  9. Glutathione

    Time frame: It was measured after 4 weeks

    antioxidant marker

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jul 21, 2021
Registry last updated
Jan 28, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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