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OpenTrials
Completed

NCT Number: NCT00741520

Cardiovascular Impact of Obstructive Sleep Apnea Treatment in Normotensive Patients

Recent evidences suggest that obstructive sleep apnea (OSA) can contribute to cardiovascular disease even in the absence of hypertension. However, there are few data regarding the impact of OSA on the preHypertension and Masked Hypertension in apparently normotensive patients with OSA as well as the impact of treatment with continuous positive airway pressure.

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Key information

Conditions

Obstructive Sleep Apnea Apnea Cardiovascular Diseases Dyssomnias Hypertension Masked Hypertension Nervous System Diseases Prehypertension Respiration Disorders Respiratory Tract Diseases Sleep Apnea Syndromes Sleep Apnea, Obstructive Sleep Disorders, Intrinsic Sleep Wake Disorders Vascular Diseases

Age range

30 year–60 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 4

Primary location

Heart Institute (InCor)

São Paulo, 05403-904, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Severe OSA patients

Exclusion criteria

  • Smoking
  • Sustained Hypertension
  • Heart failure
  • Diabetes
  • Renal diseases
  • Under use of any medication
  • Under treatment for OSA

Treatment and study plan

CPAP

Device

Control - no treatment

Primary outcomes

  1. Office Blood Pressure

    Evaluation of PreHypertension

Secondary outcomes

  1. 24 Hour Ambulatory Blood Pressure Monitoring

    Evaluation of Masked Hypertension

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Collaborators

  • Conselho Nacional de Desenvolvimento Científico e Tecnológico
  • Fundação de Amparo à Pesquisa do Estado de São Paulo

Registry information

Official study title

Cardiovascular Impact of Obstructive Sleep Apnea in Normotensive Patients and the Effects of Continuous Positive Airway Pressure

Acronym: OSA-NORMO

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Aug 26, 2008
Registry last updated
Oct 28, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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