Skip to main content
OpenTrials
Completed

NCT Number: NCT04738877

Cardiovascular Effects of Marathon Running

The aim of this study is the investigation of acute cardiovascular responses of marathon runners after the completion of a marathon race (42.2 km), as well as of the determinants of these changes.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Athletes Heart

Sex eligibility

All sexes

Study type

Observational

Primary location

Aristotle University of Thessaloniki

Thessaloniki, Greece

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Marathon runner

Exclusion criteria

  • Chronic disease, Drugs

Treatment and study plan

Body fat measurement

Diagnostic Test

Body fat measurement using skinfolds

Cardiopulmonary exercise testing

Diagnostic Test

Electrocardiographic exercise testing with ergospirometer on a treadmill

Echocardiography

Diagnostic Test

Transthoracic echocardiography

Blood test

Diagnostic Test

Blood test for measurement of haemoglobin, serum electrolytes, iron, ferritin and vitamins

Primary outcomes

  1. Baseline left ventricular (LV) systolic function

    Time frame: Evaluation of athletes within 3 weeks before the marathon running race.

    Evaluation of LV ejection fraction

  2. Baseline LV diastolic function

    Time frame: Evaluation of athletes within 3 weeks before the marathon running race.

    Evaluation of LV filling pressures

  3. Baseline basal right ventricular (RV) function

    Time frame: Evaluation of athletes within 3 weeks before the marathon running race.

    Evaluation of tricuspid annular plane systolic excursion (TAPSE)

  4. Baseline global RV function

    Time frame: Evaluation of athletes within 3 weeks before the marathon running race.

    Evaluation of RV fractional are change (RVFAC)

  5. Post-exercise LV systolic function

    Time frame: Evaluation of athletes immediately after the completion of the marathon running race.

    Evaluation of LV ejection fraction

  6. Post-exercise LV diastolic function

    Time frame: Evaluation of athletes immediately after the completion of the marathon running race.

    Evaluation of LV filling pressures

  7. Post-exercise basal RV function

    Time frame: Evaluation of athletes immediately after the completion of the marathon running race.

    Evaluation of TAPSE

  8. Post-exercise global RV function

    Time frame: Evaluation of athletes immediately after the completion of the marathon running race.

    Evaluation of RVFAC

Sponsors and collaborators

Lead sponsor

Aristotle University Of Thessaloniki

Other

Registry information

Official study title

FEIDIPIDIS Study: Cardiovascular Effects of Marathon Running

Acronym: FEIDIPIDIS

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Feb 4, 2021
Registry last updated
Nov 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.