Recruiting

NCT Number: NCT05706532

Cardiovascular and Cerebrovascular Control in Healthy Subjects

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability.

To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge.

The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Recruiting

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Key information

Conditions

Healthy Autonomic Nervous System Cerebral Autoregulation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

IRCCS Policlinico San Donato

San Donato Milanese, Milan, 20097, Italy

Location status: Recruiting

Location contact

Marco Ranucci, MD

SUB_INVESTIGATOR

Vlasta Bari, PhD

CONTACT

[email protected]

+390252774381

Vlasta Bari, PhD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age >18
sinus rhythm
informed consent signed

Exclusion criteria

age <18
presence of autonomic nervous system diseases or dysfunctions

Treatment and study plan

active standing

Diagnostic Test

Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing

Primary outcomes

Evaluate the state and interactions of autonomic function and cerebrovascular control

Time frame: 12 months

Study contacts

Contact information is provided by the study sponsor or research team.

Vlasta Bari, PhD

CONTACT

[email protected]

+390252774381

Sponsors and collaborators

Lead sponsor

IRCCS Policlinico S. Donato

Other

Registry information

Official study title

Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects

Acronym: CardioSan

Important dates

Study start: 2023
Primary completion: 2027
Study completion: 2027
First posted: Jan 31, 2023
Registry last updated: Jul 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting