Cardiopulmonary exercise testing
Diagnostic TestSubjects will undergo pre-operative cardiopulmonary exercise testing.
NCT Number: NCT06702059
Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications.
Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.
Interested in participating?
Request Info18 year and older
All sexes
Observational
Centre of Cardiovascular and Transplantation Surgery, Brno, Czech Republic, Czechia
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Subjects will undergo pre-operative cardiopulmonary exercise testing.
Time frame: within 30 post-operative days
pneumonia, atelectasis, respiratory failure, ARDS
Time frame: within 30 post-operative days
new arrhythmias (atrial fibrillation, supraventricular tachycardia, etc.), myocardial infarction/minimal myocardial lesion, hypotension, heart failure, pulmonary edema, pulmonary embolism, cardiopulmonary resuscitation
Time frame: within 30 post-operative days
Hospital and Intensive care length of stay
Contact information is provided by the study sponsor or research team.
Ivan Cundrle, prof., M.D.
CONTACT
Marek Lukes, M.D.
CONTACT
St. Anne's University Hospital Brno, Czech Republic
Other
Cardiopulmonary Exercise Testing in the Prediction of Post-operative Complications in Patients Undergoing Coronary Artery Bypass Graft Surgery
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