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Completed

NCT Number: NCT00205127

Cardiac Water and Fluoromethane Cardiac PET

In this study we are looking at the blood flow to the heart using two different chemical tags or tracers that give off a low level of radiation. The tracers used in this study are called O15-water and F17-fluoromethane. These tracers mix with the blood and will move through the body. The researchers will use positron emission tomography (PET scans)to track the tracers as they moe through the heart and chest.

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Key information

Conditions

Healthy Volunteers

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Wisconsin

Madison, Wisconsin, 53792, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Age 18 to 40 years old 2. Willing to provide written informed consent

Exclusion criteria

  • 1. A history of CAD 2. A history of active bronchospasm or asthma on theophylline bronchodilators 3. A history of any cardiac risk factors including: HTN, Diabetes, Hyperlipidemia, Smoking, and premature CAD in immediate family member 4. A history of liver disease or other significant disease 5. Females who are pregnant or lactating

Treatment and study plan

Cardiac PET imaging- rest and pharmacological stress

Procedure

Primary outcomes

  1. -- implement myocardial perfusion quantification for O15-labeled water at rest and with pharmacologic stress,

    Time frame: assess at time of PET scan

  2. -- determine the biodistribution of fluoromethane in the thorax to see if it is usable for a cardiac perfusion tracer,

    Time frame: assess at time of PET Scan

Secondary outcomes

  1. --develop initial methods for quantification of myocardial perfusion if applicable for labeled fluoromethane.

    Time frame: assess at time of PET scan

Sponsors and collaborators

Lead sponsor

University of Wisconsin, Madison

Other

Registry information

Official study title

Comparison of Cardiac Perfusion by O15-water and F17-fluoromethane PET

Important dates

Study start
2004
Primary completion
2004
Study completion
2004
First posted
Sep 20, 2005
Registry last updated
Aug 29, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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