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Completed

NCT Number: NCT06370546

Cardiac Response to Strength Training in Hypertensive Individuals

This study aims to determine the acute effects of high and low-intensity strength training on cardiac autonomic control in hypertensive subjects

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Key information

Conditions

Physical Exercise Behavior Cardiovascular Diseases Hypertension Motor Activity Vascular Diseases

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad Católica del Maule

Talca, Maule Region, 3469001, Chile

About this study

The present study aims to determine the cardiovascular response in hypertensive individuals between 30 and 60 years old to one session of high and low intensity strength training.

Participants will undergo a low-intensity strength training including squats, barbell rows, deadlifts and chest presses with a load dynamic of 12 repetitions for 6 sets at an execution speed of less than 55 % of your maximum weight. This is followed by a one-week washout period. Subsequently, high intensity strength training is performed with the same exercises but with a load of 6 repetitions for 6 series at an intensity greater than 80% of the maximum repetition speed. The order of the sessions will be random.

After each session, blood pressure will be recorded for 24 hours using a holter monitor, which will report pressures during both day and night

The results obtained will be determined by the differences in the before and after values. Consequently, the behavior of the following variables: 1) heart rate variability, 2) blood pressure and 3) heart rate will determine the final results of this research.

The entire study will be carried out at the Catholic University of Maule, in its Kinesiology laboratory.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants exclusively diagnosed with hypertension by a medical professional

Exclusion criteria

  • Participants with any other chronic medical condition
  • Subjects with any upper or lower limb injury that prevents strength training
  • Subjects with cardiovascular abnormalities other than hypertension

Treatment and study plan

Low Intensity

Other

Low intensity group: participants will be requested to perform the following exercises: 1)squat, 2) rowing, 3)deadlift and 4)bench press. All exercises will be performed with low intensity (40% of the maximum velocity used in one-repetition maximum) and will be supervised by a researcher.

High Intensity

Other

High intensity group: participants will be requested to perform the following exercises: 1)squat, 2)rowing, 3)deadlift and 4)bench press. All exercises will be performed with high intensity (80% of the maximum velocity used in one-repetition maximum) and will be supervised by a researcher.

Primary outcomes

  1. Heart rate variability

    Time frame: 2 hours

    Determine the effects of high and low-intensity strength training on heart rate variability, based on the time between each heartbeat, during the assessment

  2. Blood pressure systolic

    Time frame: 24 hours

    Determine the effects of high and low intensity resistance training on blood pressure with a blood pressure monitor for 24 hours.

  3. Blood pressure diastolic

    Time frame: 24 hours

    Determine the effects of high and low intensity resistance training on blood pressure diastolic with a blood pressure monitor for 24 hours.

  4. Blood pressure mean

    Time frame: 24 hours

    Determine the effects of high and low intensity resistance training on blood pressure mean with a blood pressure monitor for 24 hours.

  5. Heart Rate

    Time frame: 24 hours

    Determine the effects of high and low intensity strength training on the behavior of heart rate, using a heart rate monitor, throughout the intervention.

Sponsors and collaborators

Lead sponsor

Universidad Católica del Maule

Other

Registry information

Official study title

Evaluation of Cardiac Response to High and Low-Intensity Strength Training in Hypertensive Subjects

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Apr 17, 2024
Registry last updated
Sep 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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