Skip to main content
OpenTrials
Completed

NCT Number: NCT01397357

Cardiac Magnetic Resonance Utilities in the Evaluation of Ischemic Heart Disease

The purpose of this study is to evaluate CARDIAC MAGNETIC RESONANCE UTILITIES IN THE ISCHEMIC HEART DISEASE as topographical correlation between ischemic territory injury and coronary angiography.

Completed

Looking for future studies?

Notify Me

Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Maria Cecilia Hospital

Cotignola, RA, 48010, Italy

About this study

Assessing the accuracy of Cardio-RM identifying ischemic territories and their correspondence to the presence of critical coronary lesions, comparing the presence, extent and regional inducible ischaemia in the Cardiac-MRI with the presence and characteristics of vascular lesions in coronary angiography.

In particular, the study aims to evaluate the correlation between topography and function of the ischemic area revealed by the resonance and coronary artery disease documented coronary angiography.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with suspected ischemic heart disease or recurrent Myocardial ischemic symptoms defined as:
  • presence of:
  • chest pain related to the effort lasting 5-20 minutes, and / or
  • positive stress test for inducible Myocardial ischemia
  • presence of at least one of the following risk factors: smoke family history of cardiovascular disease hypertension dyslipidemia diabetes mellitus NID / ID
  • no contraindications to perform coronary angiography
  • informed written consent to the processing of personal and sensible data, signed and dated by the patient.

Exclusion criteria

  • Unstable angina;
  • Severe aortic stenosis
  • Hypertrophic cardiomyopathy
  • Pacemaker and \\ or defibrillator
  • Coronary stent implantation in 90 days before Cardiac MRI
  • Intracranial metal clips
  • Severe hypertension (systolic blood pressure> 240 mmHg, and diastolic blood pressure above 120 mmHg)
  • Ventricular thrombosis and \\ or atrial
  • Aortic aneurysm and \\ or aortic dissection
  • Myocarditis, endocarditis, pericarditis
  • Critical stenosis of the left notes
  • State of severe anxiety or claustrophobia
  • Contraindications to the use of atropine (BAV advanced glaucoma, pyloric stenosis, prostatic hypertrophy)

Treatment and study plan

Cardiac magnetic resonance - CINE MRI stress test.

Other

Cardiac magnetic resonance - dipyridamole or dobutamine MRI stress test.

Primary outcomes

  1. Accuracy of Cardio-RM identifying ischemic territories

    Time frame: 1 month

    Assessing the accuracy of Cardio-RM identifying ischemic territories and their correspondence to the presence of critical coronary lesions, comparing the presence, extent and regional inducible ischaemia in the Cardiac-MRI with the presence and characteristics of vascular lesions in coronary angiography.

Secondary outcomes

  1. correlation between resonance and coronary artery disease documented coronary angiography.

    Time frame: 1 month

    comparison of diagnostic positivity for inducible ischemia assessed by Cardiac-MRI and the presence of coronary lesions of various degrees evaluated by coronary angiography

  2. topographic correlation between ischemic territory and coronary lesions

    Time frame: 1 month

    topographic correlation between ischemic territory assessed by Cardiac-MRI and coronary lesions evaluated by coronary angiography, using the criteria defined in Sintax study and BARI study.

Sponsors and collaborators

Lead sponsor

Ettore Sansavini Health Science Foundation

Other

Registry information

Official study title

CARDIAC MAGNETIC RESONANCE UTILITIES IN THE EVALUATION OF ISCHEMIC HEART DISEASE: Topographical Correlation Between Ischemic Territory Injury and Coronary Angiography

Acronym: CARDIO-RM

Important dates

Study start
2011
Primary completion
2014
Study completion
2015
First posted
Jul 19, 2011
Registry last updated
Oct 3, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.