Cardiac-Control Affecting Learning Through Mindfulness (CALM)

Inclusion criteria

• Fluent in English
• Black/African-American or White/European-American
• Aged between 50-70 years old
• Non-pregnant and non-menstruating (for at least the past year)
• Have normal or corrected-to-normal vision and hearing
• Have reliable access to wifi
• Have an email account that you check regularly
• Have a phone that receives text messages
• Agree to provide blood and urine samples at two campus visits
• Agree to devote up to 50 minutes daily to this study for 10 weeks as well as attend two campus visits

Exclusion criteria

• Have a disorder that would impede performing the breathing intervention (e.g., abnormal cardiac rhythm, arrhythmia, dyspnea)
• Have cognitive impairment
• Have regularly played Lumosity games in the past 6 months
• Have any conditions listed below that are not safe for MRI

• *Metal in any parts of your body
• Claustrophobia
• Have worked as a machinist, metal worker, or in any profession or hobby grinding metal?
• Have had an injury to the eye involving a metallic object (e.g., metallic slivers, shavings, or foreign body)
• Cardiac pacemaker
• Implanted cardiac defibrillator
• Aneurysm clip or brain clip
• Carotid artery vascular clamp
• Neurostimulator
• Insulin or infusion pump
• Spinal fusion stimulator
• Cochlear, otologic, ear tubes or ear implant
• Prosthesis (eye/orbital, penile, etc.)
• Implant held in place by a magnet
• Heart valve prosthesis
• Artificial limb or joint
• Other implants in body or head
• Electrodes (on body, head or brain)
• Intravascular stents, filters
• Shunt (spinal or intraventricular)
• Vascular access port or catheters
• IUD
• Transdermal delivery system or other types of foil patches (e.g., Nitro, Nicotine, Birth control, etc.) that cannot be removed for MRI
• Shrapnel, buckshot, or bullets
• Tattooed eyeliner or eyebrows
• Body piercing(s) that cannot be removed for MRI
• Metal fragments (eye, head, ear, skin)
• Internal pacing wires
• Aortic clips
• Metal or wire mesh implants
• Wire sutures or surgical staples
• Harrington rods (spine)
• Bone/joint pin, screw, nail, wire, plate
• Wig or toupee that cannot be removed for MRI
• Hair implants that involve staples or metal
• Hearing aid(s) that cannot be removed for MRI
• Dentures or retainers that cannot be removed for MRI