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Completed

NCT Number: NCT03738631

Cardiac Biomarkers After Marathon Running and Coronary Atherosclerosis

This study evaluates cardiac biomarkers and their association to coronary artery disease in marathon runners.

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Key information

Conditions

Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Disease Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

35 year–90 year

Sex eligibility

Male

Study type

Observational

Primary location

Turku University Hospital, Heart Center

Turku, Finland

About this study

The MaraCat study is an observational prospective study evaluating the association between cardiac biomarkers and coronary artery disease in 43 runners participating in the 2018 Paavo Nurmi Marathon. The study participants were recruited according to two age criteria - under 35 years and over 44 years of age. Comprehensive laboratory samples were collected immediately after the run, while the control workup was done in a separate visit with no significant physical excercise in the preceding two weeks. In the under 35 years -group, the control workup included an echocardiography, ecg and blood samples. In the over 44 years group, the control studies included coronary CT, echocardiography, ecg and laboratory tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age under 35 years or over 44 years
  • Participant of Paavo Nurmi Marathon 2018
  • Informed consent signed

Exclusion criteria

  • No informed consent
  • existing coronary artery disease

Treatment and study plan

Primary outcomes

  1. Cardiac Troponin-T level after marathon

    Time frame: 0-30minutes after finishing the Paavo Nurmi Marathon

    Cardiac troponin-T levels (ng/L), [electrochemiluminescence (ECLIA) method]

  2. Association Cardiac troponin-T level and coronary CT findings

    Time frame: Cardiac Troponin-T 0-30 minutes after finishing the Paavo Nurmi Marathon. Control Troponin-T levels and coronary CT angiography at control visit (>30days after marathon).

    Cardiac troponin-T levels (ng/L), [electrochemiluminescence (ECLIA) method]

Sponsors and collaborators

Lead sponsor

University of Turku

Other

Registry information

Official study title

Association of Cardiac Biomarker Elevation After Marathon Running and Coronary Atherosclerosis - the MaraCat Study

Acronym: MaraCat

Important dates

Study start
2018
Primary completion
2022
Study completion
2022
First posted
Nov 13, 2018
Registry last updated
May 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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