Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)

PRIMARY OBJECTIVE:

I. To evaluate differences in self-reported nicotine and cannabis use behaviors and biomarkers of exposure to toxicants and carcinogens by product use status, to generate effect sizes required to calculate sample sizes needed for a larger study.

Inclusion criteria

• Young adult (18-25 years old).
• Ability to read and write in English.
• Participants must fall into one of the following groups (based on self-report):
• Predominant e-cigarette consumer: defined as using nicotine-containing e-cigarettes daily for the past six months but not having used other nicotine containing products more than weekly or cannabis products for the past month.
• Predominant cannabis consumer: defined as using cannabis at least 3x/week for the past six months in any form, including smoking, vaping, and oral use, with no more than weekly use of any nicotine or tobacco products.
• E-cigarette-cannabis co-consumers: defined as daily use of nicotine e-cigarettes and use of cannabis at least 3x/week, including smoking, vaping, and oral use, for at least the past six months, with no use of other nicotine containing products more than weekly.
• No self-reported diagnosis of kidney disease (current, or within the past year prior to the study visit).
• Participants must understand the voluntary nature of this study and sign a written informed consent form before proceeding with study activities.

Exclusion criteria

• Individuals under the age of 18 or over the age of 25.
• Currently pregnant or breastfeeding (female participants).
• Unwilling or unable to follow protocol requirements