Carbon Dioxide Insufflation Colonoscopy in IBD Patients

Carbon dioxide insufflation during colonoscopy significantly reduces discomfort (pain, bloating and flatulence) after the procedure. So far, it has not been studied in inflammatory bowel disease patients. The study was designed to evaluate discomfort after the carbon dioxide insufflation colonoscopy in comparison to standard air insufflation colonoscopy.

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Key information

Conditions

Colonoscopy Carbon Dioxide Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Inflammatory Bowel Disease Inflammatory Bowel Diseases Intestinal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Digestive Diseases Center - Vitkovice Hospital

Ostrava, 703 84, Czechia

About this study

Carbon dioxide insufflation during colonoscopy significantly reduces discomfort (pain, bloating and flatulence) during up to 24 hours after the procedure. So far, it has not been studied in inflammatory bowel disease patients who represent specific patient population indicated for colonoscopy. They are characterized by younger age, structural changes of the colon including intestinal resections and need for repeated and frequently difficult procedures.The study was designed to evaluate discomfort during 24 hours after the carbon dioxide insufflation colonoscopy in comparison to standard air insufflation colonoscopy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

known diagnosis of Crohn´s disease and ulcerative colitis
indication for diagnostic colonoscopy
informed consent
unsedated or minimally sedated procedure (< 3 mg of midazolam)

Exclusion criteria

planned incomplete or therapeutic procedure
deep sedation or general anesthesia
intestinal resection longer than ileocecal resection
isolated gastroduodenal or jejunal location of Crohn´s disease (L4)
ulcerative proctitis (E1)

Treatment and study plan

Carbon dioxide insufflation

Procedure

Carbon dioxide insufflation during diagnostic colonoscopy

Primary outcomes

Bloating score 1 hour after the colonoscopy

Time frame: 1 hour

Bloating severity on continuous scale 0-10 (0 = none, 10 = worst) 1 hour after colonoscopy

Sponsors and collaborators

Lead sponsor

Vitkovice Hospital

Other

Registry information

Official study title

Carbon Dioxide Insufflation Colonoscopy in Inflammatory Bowel Disease Patients

Important dates

Study start: 2015
Primary completion: 2016
Study completion: 2016
First posted: Sep 29, 2015
Registry last updated: Jun 1, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed