Canola Oil Multi-center Intervention Trial II

Inclusion criteria

• waist circumference ≥94 cm for men and ≥80 cm for women
• Elevated triglycerides - ≥150 mg/dL and ≤ 400 mg/dL
• Reduced HDL - < 40 mg/dL for men and < 50 mg/dL for women
• Fasting glucose - ≥ 100 mg/dl and ≤ 126 mg/dL
• Elevated blood pressure - systolic ≥130 and/or diastolic ≥85 mm HG [Unmedicated participants - upper limit of Stage 1 Hypertension: systolic < 160 and/or diastolic <100 mm HG and participants must be free of end stage/target organ disease symptoms] [BP medicated participants: acceptable as long as individuals meet the specified blood pressure range of <140/90 mmHg, and have been stable for at least 6 months]

Exclusion criteria

• Individuals with thyroid**, kidney, or liver disease [Individuals with thyroid disease whose blood values are within normal limits and that have been stable (on medication) for the past 6 months are considered eligible]
• Individuals with diabetes mellitus
• Smokers
• Individuals consuming >14 alcoholic beverages per week
• Individuals taking lipid lowering medication (ex: cholestyramine, colestipol, niacin, cloribrate, gemfibrozil, probucol, HMG CoA reductase inhibitors) for at least the last 3 months
• Pregnancy or lactation