Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT04567394

Cannabis Use Disorder Treatment Study

The purpose of this study is to test a text-delivered counseling program to stop or reduce cannabis use among young adults (ages 18 to 25).

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Cannabis Use Disorder, Mild Cannabis Use Disorder, Moderate Cannabis Use Disorder, Severe Hemic and Lymphatic Diseases Immune System Diseases Immunoproliferative Disorders Lymphatic Diseases Lymphoma Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoproliferative Disorders Neoplasms Neoplasms by Histologic Type

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Colorado State University, Fort Collins, Colorado, United States

Loading trial locations.

About this study

After being informed about the study and potential risks, participants will complete online screening assessments. Those who are determined to be eligible via online screening will complete a urine drug screen to confirm eligibility. Once eligibility is confirmed, participants will be randomized either to the intervention group or to the wait-list control group. Those who are randomized to the intervention group will receive the 4-week text intervention via smartphone and complete assessments (including urine drug screens) at baseline, 1 month, 3 months, and 6 months. Those who are randomized to the wait-list control group will only complete the assessments (including urine drug screens) at baseline, 1 month, 3 months, and 6 months. Participants who are initially assigned to the wait-list control group can choose to receive the text intervention once their 6-month participation is complete.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 to 25 years old.
  • use of cannabis three or more days during a typical week.
  • a score of at least eight on the Cannabis Use Disorder Identification Test-Revised
  • a urine specimen positive for cannabis metabolites.
  • a score of at least two on the Mini International Neuropsychiatric Interview: Version 7.0.2 for DSM-V, Substance Use Disorder
  • must live in Tennessee or Colorado

Exclusion criteria

  • substance abuse treatment during the past three months.
  • lack of access to a text-capable phone.
  • unable or unwilling to commit to six months of follow-up.
  • not fluent in English.

Treatment and study plan

Peer Network Counseling-txt

Behavioral

4-week text counseling program

Other names: PNC-txt

Primary outcomes

  1. Change from Baseline in Tetrahydrocannabinol (Delta-9-THC-COOH) levels

    Time frame: Baseline, 1 month, 3 months, 6 months

    Urine THC levels (50ng/mL, 100ng/mL, 200ng/mL, 300ng/mL) will provide a biological measure for current cannabis use.

  2. Change in Past 30-Day Cannabis Use

    Time frame: Baseline, 1 month, 3 months, 6 months

    Past-30-day substance use (cannabis, alcohol, tobacco, other drugs) and consequences are measured using the Alcohol, Smoking and Substance Involvement Screening Test

Secondary outcomes

  1. Change in Environmental Risk Assessment

    Time frame: Baseline, 1 month, 3 months, 6 months

    Participants will report using the Ecological Momentary Assessment reporting about Craving (0=none-10= intense), Cannabis Use (0=none-10= a lot), Mood (0=very good-10= very depressed), and Stress (0=no stress-10 = very stressed) on a 10 point scale for each item

  2. Change in Young Adult Social Network Assessment

    Time frame: Baseline, 1 month, 3 months, 6 months

    Participants report information on each their 3 closest friends, representing their egocentric network. Individual friend scores are totaled based on all 8 risky and prosocial items (2-9). Thus, each peer's score has a potential range from -32 to 32, with greater scores indicating a healthier relationship. The total peer network health scores is based on the sum of all 24 risky and prosocial items across all three friends. Assuming three peers per participant, total network quality scores may range from -96 to 96, with lower scores indicating greater network risk and higher scores indicating greater network protection.

  3. Cost Measures

    Time frame: 6 months

    Cost of intervention implementation will be compared to typical treatment cost for cannabis use disorder

Sponsors and collaborators

Lead sponsor

The University of Tennessee, Knoxville

Other

Collaborators

  • Colorado State University

Registry information

Official study title

Treating Young Adult Cannabis Use Disorder With Text Message-Delivered Peer Network Counseling

Important dates

Study start
2019
Primary completion
2026
Study completion
2026
First posted
Sep 28, 2020
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.